Reproduction number and sensitivity analysis of cassava mosaic disease spread for policy design
We develop a mathematical model for the dynamics of Cassava Mosaic Disease (CMD), which is driven by both planting of infected cuttings and whitefly transmission. We use the model to analyze the dynamics of a CMD outbreak and to identify the most cost-effective policy for controlling it. The model u...
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2021
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oai:doaj.org-article:764bd0d1bb87433883b2b366979ec76b2021-11-08T03:10:10ZReproduction number and sensitivity analysis of cassava mosaic disease spread for policy design10.3934/mbe.20212581551-0018https://doaj.org/article/764bd0d1bb87433883b2b366979ec76b2021-06-01T00:00:00Zhttps://www.aimspress.com/article/doi/10.3934/mbe.2021258?viewType=HTMLhttps://doaj.org/toc/1551-0018We develop a mathematical model for the dynamics of Cassava Mosaic Disease (CMD), which is driven by both planting of infected cuttings and whitefly transmission. We use the model to analyze the dynamics of a CMD outbreak and to identify the most cost-effective policy for controlling it. The model uses the reproduction number $ \mathscr{R}_0 $ as a threshold, calculated using the Next-Generation Method. A locally-asymptotically-stable disease-free equilibrium is established when $ \mathscr{R}_0 < 1 $, proved by the Routh-Hurwitz criterion. The globally-asymptotically-stable disease-free and endemic-equilibrium points are obtained using Lyapunov's method and LaSalle's invariance principle. Our results indicate that the disease-free equilibrium point is globally-asymptotically-stable when $ \mathscr{R}_0 \leq 1 $, while the endemic-equilibrium point is globally-asymptotically-stable when $ \mathscr{R}_0 > 1 $. Our sensitivity analysis shows that $ \mathscr{R}_0 $ is most sensitive to the density of whitefly. Numerical simulations confirmed the effectiveness of whitefly control for limiting an outbreak while minimizing costs.Phongchai JittamaiNatdanai ChanlawongWanyok AtisattapongWanwarat Anlamlert Natthiya Buensanteai AIMS Pressarticlecassava mosaic disease (cmd)reproduction numberlocal stabilityglobal stabilitysensitivity analysisBiotechnologyTP248.13-248.65MathematicsQA1-939ENMathematical Biosciences and Engineering, Vol 18, Iss 5, Pp 5069-5093 (2021) |
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cassava mosaic disease (cmd) reproduction number local stability global stability sensitivity analysis Biotechnology TP248.13-248.65 Mathematics QA1-939 |
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cassava mosaic disease (cmd) reproduction number local stability global stability sensitivity analysis Biotechnology TP248.13-248.65 Mathematics QA1-939 Phongchai Jittamai Natdanai Chanlawong Wanyok Atisattapong Wanwarat Anlamlert Natthiya Buensanteai Reproduction number and sensitivity analysis of cassava mosaic disease spread for policy design |
| description |
We develop a mathematical model for the dynamics of Cassava Mosaic Disease (CMD), which is driven by both planting of infected cuttings and whitefly transmission. We use the model to analyze the dynamics of a CMD outbreak and to identify the most cost-effective policy for controlling it. The model uses the reproduction number $ \mathscr{R}_0 $ as a threshold, calculated using the Next-Generation Method. A locally-asymptotically-stable disease-free equilibrium is established when $ \mathscr{R}_0 < 1 $, proved by the Routh-Hurwitz criterion. The globally-asymptotically-stable disease-free and endemic-equilibrium points are obtained using Lyapunov's method and LaSalle's invariance principle. Our results indicate that the disease-free equilibrium point is globally-asymptotically-stable when $ \mathscr{R}_0 \leq 1 $, while the endemic-equilibrium point is globally-asymptotically-stable when $ \mathscr{R}_0 > 1 $. Our sensitivity analysis shows that $ \mathscr{R}_0 $ is most sensitive to the density of whitefly. Numerical simulations confirmed the effectiveness of whitefly control for limiting an outbreak while minimizing costs. |
| format |
article |
| author |
Phongchai Jittamai Natdanai Chanlawong Wanyok Atisattapong Wanwarat Anlamlert Natthiya Buensanteai |
| author_facet |
Phongchai Jittamai Natdanai Chanlawong Wanyok Atisattapong Wanwarat Anlamlert Natthiya Buensanteai |
| author_sort |
Phongchai Jittamai |
| title |
Reproduction number and sensitivity analysis of cassava mosaic disease spread for policy design |
| title_short |
Reproduction number and sensitivity analysis of cassava mosaic disease spread for policy design |
| title_full |
Reproduction number and sensitivity analysis of cassava mosaic disease spread for policy design |
| title_fullStr |
Reproduction number and sensitivity analysis of cassava mosaic disease spread for policy design |
| title_full_unstemmed |
Reproduction number and sensitivity analysis of cassava mosaic disease spread for policy design |
| title_sort |
reproduction number and sensitivity analysis of cassava mosaic disease spread for policy design |
| publisher |
AIMS Press |
| publishDate |
2021 |
| url |
https://doaj.org/article/764bd0d1bb87433883b2b366979ec76b |
| work_keys_str_mv |
AT phongchaijittamai reproductionnumberandsensitivityanalysisofcassavamosaicdiseasespreadforpolicydesign AT natdanaichanlawong reproductionnumberandsensitivityanalysisofcassavamosaicdiseasespreadforpolicydesign AT wanyokatisattapong reproductionnumberandsensitivityanalysisofcassavamosaicdiseasespreadforpolicydesign AT wanwaratanlamlert reproductionnumberandsensitivityanalysisofcassavamosaicdiseasespreadforpolicydesign AT natthiyabuensanteai reproductionnumberandsensitivityanalysisofcassavamosaicdiseasespreadforpolicydesign |
| _version_ |
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