Cyclosporine A Induces Cardiac Developmental Toxicity in Zebrafish by Up-Regulation of Wnt Signaling and Oxidative Stress
Due to the widely application of Cyclosporine A (CsA) as an immunosuppressant in clinic, it is necessary to study its potential toxicity. Therefore, we used zebrafish as a model animal to evaluate the toxicity of CsA on embryonic development. Exposure of zebrafish embryos to CsA at concentrations of...
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Auteurs principaux: | Mengqi Wan, Ling Huang, Jieping Liu, Fasheng Liu, Guilan Chen, Huiwen Ni, Guanghua Xiong, Xinjun Liao, Huiqiang Lu, Juhua Xiao, Qiang Tao, Zigang Cao |
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Format: | article |
Langue: | EN |
Publié: |
Frontiers Media S.A.
2021
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Accès en ligne: | https://doaj.org/article/7655dadcd85841d0a724e67bbafe2ed6 |
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