The Fusion of CLEC12A and MIR223HG Arises from a trans-Splicing Event in Normal and Transformed Human Cells

Chimeric RNAs are often associated with chromosomal rearrangements in cancer. In addition, they are also widely detected in normal tissues, contributing to transcriptomic complexity. Despite their prevalence, little is known about the characteristics and functions of chimeric RNAs. Here, we examine...

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Autores principales:	Bijay P. Dhungel, Geoffray Monteuuis, Caroline Giardina, Mehdi S. Tabar, Yue Feng, Cynthia Metierre, Sarah Ho, Rajini Nagarajah, Angela R. M. Fontaine, Jaynish S. Shah, Divya Gokal, Charles G. Bailey, Ulf Schmitz, John E. J. Rasko
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	chimeric RNAs Fusion RNAs encoding protein fusion transcript linc-223 miR-223 host gene trans-splicing Biology (General) QH301-705.5 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/76580557ad97406c8cd6513f7e7d7f09
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The Fusion of <i>CLEC12A</i> and <i>MIR223HG</i> Arises from a <i>trans</i>-Splicing Event in Normal and Transformed Human Cells

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