The role of pathological tau in synaptic dysfunction in Alzheimer’s diseases
Abstract Alzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive cognitive decline, accompanied by amyloid-β (Aβ) overload and hyperphosphorylated tau accumulation in the brain. Synaptic dysfunction, an important pathological hallmark in AD, is recognized as the main cau...
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Main Authors: | , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
BMC
2021
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Subjects: | |
Online Access: | https://doaj.org/article/765eab5126d74de6b3567f70393b2d75 |
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