Scientific Evidence of Xuebijing Injection in the Treatment of Sepsis

Objectives. To systematically collate, appraise, and synthesize the current evidence on the Xuebijing injection (XBJI) for sepsis. Methods. Eight databases were searched for systematic reviews (SRs) or meta-analyses (MAs) on XBJI for sepsis. Assessing the Methodological Quality of Systematic Reviews...

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Autores principales:	Sa Tian, Defang Qin, Yixuan Ye, Huawei Yang, Shuguang Chen, Tao Liu, Luming Hu, Huiming Li, Qian Niu, Xingzhan Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Other systems of medicine RZ201-999
Acceso en línea:	https://doaj.org/article/76667ccadb9f4eafbab92b5ec7cbbc66
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spelling	oai:doaj.org-article:76667ccadb9f4eafbab92b5ec7cbbc662021-11-08T02:36:01ZScientific Evidence of Xuebijing Injection in the Treatment of Sepsis1741-428810.1155/2021/6879278https://doaj.org/article/76667ccadb9f4eafbab92b5ec7cbbc662021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/6879278https://doaj.org/toc/1741-4288Objectives. To systematically collate, appraise, and synthesize the current evidence on the Xuebijing injection (XBJI) for sepsis. Methods. Eight databases were searched for systematic reviews (SRs) or meta-analyses (MAs) on XBJI for sepsis. Assessing the Methodological Quality of Systematic Reviews-2 (AMSTAR-2), Preferred Reporting Item for Systematic Reviews and Meta-Analyses (PRISMA), and Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methods were used to assess the methodological quality, reporting quality, and evidence quality of the enrolled studies, respectively. Results. Out of the 13 studies that were included, all studies were rated critically low quality based on AMSTAR-2 results. Based on the results obtained from PRISMA, all studies were reported to be over 80%, while the GRADE system yielded three outcome measures rated high-quality, 16 were of moderate quality, and the rest were of low or critically low quality. Conclusions. The combination of XBJI and Western medicine (WM) showed significant synergy for the treatment of sepsis compared to WM alone. However, this conclusion should be treated with caution since the quality of the SRs/MAs providing the evidence was relatively low.Sa TianDefang QinYixuan YeHuawei YangShuguang ChenTao LiuLuming HuHuiming LiQian NiuXingzhan ZhangHindawi LimitedarticleOther systems of medicineRZ201-999ENEvidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Other systems of medicine RZ201-999
spellingShingle	Other systems of medicine RZ201-999 Sa Tian Defang Qin Yixuan Ye Huawei Yang Shuguang Chen Tao Liu Luming Hu Huiming Li Qian Niu Xingzhan Zhang Scientific Evidence of Xuebijing Injection in the Treatment of Sepsis
description	Objectives. To systematically collate, appraise, and synthesize the current evidence on the Xuebijing injection (XBJI) for sepsis. Methods. Eight databases were searched for systematic reviews (SRs) or meta-analyses (MAs) on XBJI for sepsis. Assessing the Methodological Quality of Systematic Reviews-2 (AMSTAR-2), Preferred Reporting Item for Systematic Reviews and Meta-Analyses (PRISMA), and Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methods were used to assess the methodological quality, reporting quality, and evidence quality of the enrolled studies, respectively. Results. Out of the 13 studies that were included, all studies were rated critically low quality based on AMSTAR-2 results. Based on the results obtained from PRISMA, all studies were reported to be over 80%, while the GRADE system yielded three outcome measures rated high-quality, 16 were of moderate quality, and the rest were of low or critically low quality. Conclusions. The combination of XBJI and Western medicine (WM) showed significant synergy for the treatment of sepsis compared to WM alone. However, this conclusion should be treated with caution since the quality of the SRs/MAs providing the evidence was relatively low.
format	article
author	Sa Tian Defang Qin Yixuan Ye Huawei Yang Shuguang Chen Tao Liu Luming Hu Huiming Li Qian Niu Xingzhan Zhang
author_facet	Sa Tian Defang Qin Yixuan Ye Huawei Yang Shuguang Chen Tao Liu Luming Hu Huiming Li Qian Niu Xingzhan Zhang
author_sort	Sa Tian
title	Scientific Evidence of Xuebijing Injection in the Treatment of Sepsis
title_short	Scientific Evidence of Xuebijing Injection in the Treatment of Sepsis
title_full	Scientific Evidence of Xuebijing Injection in the Treatment of Sepsis
title_fullStr	Scientific Evidence of Xuebijing Injection in the Treatment of Sepsis
title_full_unstemmed	Scientific Evidence of Xuebijing Injection in the Treatment of Sepsis
title_sort	scientific evidence of xuebijing injection in the treatment of sepsis
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/76667ccadb9f4eafbab92b5ec7cbbc66
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Scientific Evidence of Xuebijing Injection in the Treatment of Sepsis

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