Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii
Cortical microtubules of Toxoplasma gondii are exceptionally stable, but it isn’t known how they are anchored along membranes. Here, Harding et al. show that GAPM proteins localize to the inner membrane complex and are essential for maintaining the structural stability of parasites.
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Nature Portfolio
2019
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oai:doaj.org-article:766fd260c7ed44caaa4862fd02dabe792021-12-02T17:02:07ZAlveolar proteins stabilize cortical microtubules in Toxoplasma gondii10.1038/s41467-019-08318-72041-1723https://doaj.org/article/766fd260c7ed44caaa4862fd02dabe792019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08318-7https://doaj.org/toc/2041-1723Cortical microtubules of Toxoplasma gondii are exceptionally stable, but it isn’t known how they are anchored along membranes. Here, Harding et al. show that GAPM proteins localize to the inner membrane complex and are essential for maintaining the structural stability of parasites.Clare R. HardingMatthew GowJoon Ho KangEmily ShorttScott R. ManalisMarkus MeissnerSebastian LouridoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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Science Q Clare R. Harding Matthew Gow Joon Ho Kang Emily Shortt Scott R. Manalis Markus Meissner Sebastian Lourido Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii |
description |
Cortical microtubules of Toxoplasma gondii are exceptionally stable, but it isn’t known how they are anchored along membranes. Here, Harding et al. show that GAPM proteins localize to the inner membrane complex and are essential for maintaining the structural stability of parasites. |
format |
article |
author |
Clare R. Harding Matthew Gow Joon Ho Kang Emily Shortt Scott R. Manalis Markus Meissner Sebastian Lourido |
author_facet |
Clare R. Harding Matthew Gow Joon Ho Kang Emily Shortt Scott R. Manalis Markus Meissner Sebastian Lourido |
author_sort |
Clare R. Harding |
title |
Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii |
title_short |
Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii |
title_full |
Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii |
title_fullStr |
Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii |
title_full_unstemmed |
Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii |
title_sort |
alveolar proteins stabilize cortical microtubules in toxoplasma gondii |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/766fd260c7ed44caaa4862fd02dabe79 |
work_keys_str_mv |
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_version_ |
1718381975814799360 |