Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii

Cortical microtubules of Toxoplasma gondii are exceptionally stable, but it isn’t known how they are anchored along membranes. Here, Harding et al. show that GAPM proteins localize to the inner membrane complex and are essential for maintaining the structural stability of parasites.

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Autores principales: Clare R. Harding, Matthew Gow, Joon Ho Kang, Emily Shortt, Scott R. Manalis, Markus Meissner, Sebastian Lourido
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/766fd260c7ed44caaa4862fd02dabe79
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spelling oai:doaj.org-article:766fd260c7ed44caaa4862fd02dabe792021-12-02T17:02:07ZAlveolar proteins stabilize cortical microtubules in Toxoplasma gondii10.1038/s41467-019-08318-72041-1723https://doaj.org/article/766fd260c7ed44caaa4862fd02dabe792019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08318-7https://doaj.org/toc/2041-1723Cortical microtubules of Toxoplasma gondii are exceptionally stable, but it isn’t known how they are anchored along membranes. Here, Harding et al. show that GAPM proteins localize to the inner membrane complex and are essential for maintaining the structural stability of parasites.Clare R. HardingMatthew GowJoon Ho KangEmily ShorttScott R. ManalisMarkus MeissnerSebastian LouridoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Clare R. Harding
Matthew Gow
Joon Ho Kang
Emily Shortt
Scott R. Manalis
Markus Meissner
Sebastian Lourido
Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii
description Cortical microtubules of Toxoplasma gondii are exceptionally stable, but it isn’t known how they are anchored along membranes. Here, Harding et al. show that GAPM proteins localize to the inner membrane complex and are essential for maintaining the structural stability of parasites.
format article
author Clare R. Harding
Matthew Gow
Joon Ho Kang
Emily Shortt
Scott R. Manalis
Markus Meissner
Sebastian Lourido
author_facet Clare R. Harding
Matthew Gow
Joon Ho Kang
Emily Shortt
Scott R. Manalis
Markus Meissner
Sebastian Lourido
author_sort Clare R. Harding
title Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii
title_short Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii
title_full Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii
title_fullStr Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii
title_full_unstemmed Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii
title_sort alveolar proteins stabilize cortical microtubules in toxoplasma gondii
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/766fd260c7ed44caaa4862fd02dabe79
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