Increased Ndfip1 in the substantia nigra of Parkinsonian brains is associated with elevated iron levels.

Increased Ndfip1 in the substantia nigra of Parkinsonian brains is associated with elevated iron levels.

Iron misregulation is a central component in the neuropathology of Parkinson's disease. The iron transport protein DMT1 is known to be increased in Parkinson's brains linking functional transport mechanisms with iron accumulation. The regulation of DMT1 is therefore critical to the managem...

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Autores principales: Jason Howitt, Amanda M Gysbers, Scott Ayton, Francine Carew-Jones, Ulrich Putz, David I Finkelstein, Glenda M Halliday, Seong-Seng Tan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/767b3a60127b4941bb2af571c32d443e
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