Assessment of Delivery Quality Assurance for Stereotactic Radiosurgery With Cyberknife

PurposeThe purpose of this study is to establish and assess a practical delivery quality assurance method for stereotactic radiosurgery with Cyberknife by analyzing the geometric and dosimetric accuracies obtained using a PTW31016 PinPoint ionization chamber and EBT3 films. Moreover, this study also...

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Autores principales:	Jun Li, Xile Zhang, Yuxi Pan, Hongqing Zhuang, Junjie Wang, Ruijie Yang
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	delivery quality assurance Cyberknife small field ionization chamber EBT3 film Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/769162ddd861449b994ca21578fbe987
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spelling	oai:doaj.org-article:769162ddd861449b994ca21578fbe9872021-11-17T04:59:18ZAssessment of Delivery Quality Assurance for Stereotactic Radiosurgery With Cyberknife2234-943X10.3389/fonc.2021.751922https://doaj.org/article/769162ddd861449b994ca21578fbe9872021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.751922/fullhttps://doaj.org/toc/2234-943XPurposeThe purpose of this study is to establish and assess a practical delivery quality assurance method for stereotactic radiosurgery with Cyberknife by analyzing the geometric and dosimetric accuracies obtained using a PTW31016 PinPoint ionization chamber and EBT3 films. Moreover, this study also explores the relationship between the parameters of plan complexity, target volume, and deliverability parameters and provides a valuable reference for improving plan optimization and validation.MethodsOne hundred fifty cases of delivery quality assurance plans were performed on Cyberknife to assess point dose and planar dose distribution, respectively, using a PTW31016 PinPoint ionization chamber and Gafchromic EBT3 films. The measured chamber doses were compared with the planned mean doses in the sensitive volume of the chamber, and the measured planar doses were compared with the calculated dose distribution using gamma index analysis. The gamma passing rates were evaluated using the criteria of 3%/1 mm and 2%/2 mm. The statistical significance of the correlations between the complexity metrics, target volume, and the gamma passing rate were analyzed using Spearman’s rank correlation coefficient.ResultsFor point dose comparison, the averaged dose differences (± standard deviations) were 1.6 ± 0.73% for all the cases. For planar dose distribution, the mean gamma passing rate for 3%/1 mm, and 2%/2 mm evaluation criteria were 94.26% ± 1.89%, and 93.86% ± 2.16%, respectively. The gamma passing rates were higher than 90% for all the delivery quality assurance plans with the criteria of 3%/1 mm and 2%/2 mm. The difference in point dose was lowly correlated with volume of PTV, number of beams, and treatment time for 150 DQA plans, and highly correlated with volume of PTV for 18 DQA plans of small target. DQA gamma passing rate (2%/2 mm) was a moderate significant correlation for the number of nodes, number of beams and treatment time, and a low correlation with MU.ConclusionPTW31016 PinPoint ionization chamber and EBT3 film can be used for routine Cyberknife delivery quality assurance. The point dose difference should be within 3%. The gamma passing rate should be higher than 90% for the criteria of 3%/1 mm and 2%/2 mm. In addition, the plan complexity and PTV volume were found to have some influence on the plan deliverability.Jun LiXile ZhangYuxi PanHongqing ZhuangJunjie WangRuijie YangFrontiers Media S.A.articledelivery quality assuranceCyberknifesmall fieldionization chamberEBT3 filmNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	delivery quality assurance Cyberknife small field ionization chamber EBT3 film Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	delivery quality assurance Cyberknife small field ionization chamber EBT3 film Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Jun Li Xile Zhang Yuxi Pan Hongqing Zhuang Junjie Wang Ruijie Yang Assessment of Delivery Quality Assurance for Stereotactic Radiosurgery With Cyberknife
description	PurposeThe purpose of this study is to establish and assess a practical delivery quality assurance method for stereotactic radiosurgery with Cyberknife by analyzing the geometric and dosimetric accuracies obtained using a PTW31016 PinPoint ionization chamber and EBT3 films. Moreover, this study also explores the relationship between the parameters of plan complexity, target volume, and deliverability parameters and provides a valuable reference for improving plan optimization and validation.MethodsOne hundred fifty cases of delivery quality assurance plans were performed on Cyberknife to assess point dose and planar dose distribution, respectively, using a PTW31016 PinPoint ionization chamber and Gafchromic EBT3 films. The measured chamber doses were compared with the planned mean doses in the sensitive volume of the chamber, and the measured planar doses were compared with the calculated dose distribution using gamma index analysis. The gamma passing rates were evaluated using the criteria of 3%/1 mm and 2%/2 mm. The statistical significance of the correlations between the complexity metrics, target volume, and the gamma passing rate were analyzed using Spearman’s rank correlation coefficient.ResultsFor point dose comparison, the averaged dose differences (± standard deviations) were 1.6 ± 0.73% for all the cases. For planar dose distribution, the mean gamma passing rate for 3%/1 mm, and 2%/2 mm evaluation criteria were 94.26% ± 1.89%, and 93.86% ± 2.16%, respectively. The gamma passing rates were higher than 90% for all the delivery quality assurance plans with the criteria of 3%/1 mm and 2%/2 mm. The difference in point dose was lowly correlated with volume of PTV, number of beams, and treatment time for 150 DQA plans, and highly correlated with volume of PTV for 18 DQA plans of small target. DQA gamma passing rate (2%/2 mm) was a moderate significant correlation for the number of nodes, number of beams and treatment time, and a low correlation with MU.ConclusionPTW31016 PinPoint ionization chamber and EBT3 film can be used for routine Cyberknife delivery quality assurance. The point dose difference should be within 3%. The gamma passing rate should be higher than 90% for the criteria of 3%/1 mm and 2%/2 mm. In addition, the plan complexity and PTV volume were found to have some influence on the plan deliverability.
format	article
author	Jun Li Xile Zhang Yuxi Pan Hongqing Zhuang Junjie Wang Ruijie Yang
author_facet	Jun Li Xile Zhang Yuxi Pan Hongqing Zhuang Junjie Wang Ruijie Yang
author_sort	Jun Li
title	Assessment of Delivery Quality Assurance for Stereotactic Radiosurgery With Cyberknife
title_short	Assessment of Delivery Quality Assurance for Stereotactic Radiosurgery With Cyberknife
title_full	Assessment of Delivery Quality Assurance for Stereotactic Radiosurgery With Cyberknife
title_fullStr	Assessment of Delivery Quality Assurance for Stereotactic Radiosurgery With Cyberknife
title_full_unstemmed	Assessment of Delivery Quality Assurance for Stereotactic Radiosurgery With Cyberknife
title_sort	assessment of delivery quality assurance for stereotactic radiosurgery with cyberknife
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/769162ddd861449b994ca21578fbe987
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Assessment of Delivery Quality Assurance for Stereotactic Radiosurgery With Cyberknife

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