Characterization of a Replication-Incompetent Pseudorabies Virus Mutant Lacking the Sole Immediate Early Gene IE180

ABSTRACT The alphaherpesvirus pseudorabies virus (PRV) encodes a single immediate early gene called IE180. The IE180 protein is a potent transcriptional activator of viral genes involved in DNA replication and RNA transcription. A PRV mutant with both copies of IE180 deleted was constructed 20 years...

Full description

Saved in:
Bibliographic Details
Main Authors: Brendan W. Wu, Esteban A. Engel, Lynn W. Enquist
Format: article
Language:EN
Published: American Society for Microbiology 2014
Subjects:
Online Access:https://doaj.org/article/7691c243ed894e978bbe7f74c926cfba
Tags: Add Tag
No Tags, Be the first to tag this record!