Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.

Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.

TRPM6 and TRPM7 are bifunctional proteins expressing a TRP channel fused to an atypical alpha-kinase domain. While the gating properties of TRPM6 and TRPM7 channels have been studied in detail, little is known about the mechanisms regulating kinase activity. Recently, we found that TRPM7 associates...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kristopher Clark, Jeroen Middelbeek, Nick A Morrice, Carl G Figdor, Edwin Lasonder, Frank N van Leeuwen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/7698f9dc761844ae84244a5b619b0d9f
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares