Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal
Extracellular matrix (ECM) remodelling is thought to have effects on muscle stem cells that support muscle homeostasis. Here the authors show ECM remodeling controls satellite cell self-renewal through deposition of laminin-α1 into the satellite cell niche.
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Nature Portfolio
2018
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oai:doaj.org-article:769c8e79a91d443abc08b2d2575d38d82021-12-02T15:34:18ZBasal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal10.1038/s41467-018-03425-32041-1723https://doaj.org/article/769c8e79a91d443abc08b2d2575d38d82018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03425-3https://doaj.org/toc/2041-1723Extracellular matrix (ECM) remodelling is thought to have effects on muscle stem cells that support muscle homeostasis. Here the authors show ECM remodeling controls satellite cell self-renewal through deposition of laminin-α1 into the satellite cell niche.Shantisree Sandeepani RayagiriDaniele RanaldiAlexander RavenNur Izzah Farhana Mohamad AzharOlivier LefebvrePeter S ZammitAnne-Gaëlle BoryckiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Shantisree Sandeepani Rayagiri Daniele Ranaldi Alexander Raven Nur Izzah Farhana Mohamad Azhar Olivier Lefebvre Peter S Zammit Anne-Gaëlle Borycki Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal |
description |
Extracellular matrix (ECM) remodelling is thought to have effects on muscle stem cells that support muscle homeostasis. Here the authors show ECM remodeling controls satellite cell self-renewal through deposition of laminin-α1 into the satellite cell niche. |
format |
article |
author |
Shantisree Sandeepani Rayagiri Daniele Ranaldi Alexander Raven Nur Izzah Farhana Mohamad Azhar Olivier Lefebvre Peter S Zammit Anne-Gaëlle Borycki |
author_facet |
Shantisree Sandeepani Rayagiri Daniele Ranaldi Alexander Raven Nur Izzah Farhana Mohamad Azhar Olivier Lefebvre Peter S Zammit Anne-Gaëlle Borycki |
author_sort |
Shantisree Sandeepani Rayagiri |
title |
Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal |
title_short |
Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal |
title_full |
Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal |
title_fullStr |
Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal |
title_full_unstemmed |
Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal |
title_sort |
basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/769c8e79a91d443abc08b2d2575d38d8 |
work_keys_str_mv |
AT shantisreesandeepanirayagiri basallaminaremodelingattheskeletalmusclestemcellnichemediatesstemcellselfrenewal AT danieleranaldi basallaminaremodelingattheskeletalmusclestemcellnichemediatesstemcellselfrenewal AT alexanderraven basallaminaremodelingattheskeletalmusclestemcellnichemediatesstemcellselfrenewal AT nurizzahfarhanamohamadazhar basallaminaremodelingattheskeletalmusclestemcellnichemediatesstemcellselfrenewal AT olivierlefebvre basallaminaremodelingattheskeletalmusclestemcellnichemediatesstemcellselfrenewal AT peterszammit basallaminaremodelingattheskeletalmusclestemcellnichemediatesstemcellselfrenewal AT annegaelleborycki basallaminaremodelingattheskeletalmusclestemcellnichemediatesstemcellselfrenewal |
_version_ |
1718386908078276608 |