Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal

Extracellular matrix (ECM) remodelling is thought to have effects on muscle stem cells that support muscle homeostasis. Here the authors show ECM remodeling controls satellite cell self-renewal through deposition of laminin-α1 into the satellite cell niche.

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Autores principales: Shantisree Sandeepani Rayagiri, Daniele Ranaldi, Alexander Raven, Nur Izzah Farhana Mohamad Azhar, Olivier Lefebvre, Peter S Zammit, Anne-Gaëlle Borycki
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/769c8e79a91d443abc08b2d2575d38d8
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spelling oai:doaj.org-article:769c8e79a91d443abc08b2d2575d38d82021-12-02T15:34:18ZBasal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal10.1038/s41467-018-03425-32041-1723https://doaj.org/article/769c8e79a91d443abc08b2d2575d38d82018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03425-3https://doaj.org/toc/2041-1723Extracellular matrix (ECM) remodelling is thought to have effects on muscle stem cells that support muscle homeostasis. Here the authors show ECM remodeling controls satellite cell self-renewal through deposition of laminin-α1 into the satellite cell niche.Shantisree Sandeepani RayagiriDaniele RanaldiAlexander RavenNur Izzah Farhana Mohamad AzharOlivier LefebvrePeter S ZammitAnne-Gaëlle BoryckiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shantisree Sandeepani Rayagiri
Daniele Ranaldi
Alexander Raven
Nur Izzah Farhana Mohamad Azhar
Olivier Lefebvre
Peter S Zammit
Anne-Gaëlle Borycki
Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal
description Extracellular matrix (ECM) remodelling is thought to have effects on muscle stem cells that support muscle homeostasis. Here the authors show ECM remodeling controls satellite cell self-renewal through deposition of laminin-α1 into the satellite cell niche.
format article
author Shantisree Sandeepani Rayagiri
Daniele Ranaldi
Alexander Raven
Nur Izzah Farhana Mohamad Azhar
Olivier Lefebvre
Peter S Zammit
Anne-Gaëlle Borycki
author_facet Shantisree Sandeepani Rayagiri
Daniele Ranaldi
Alexander Raven
Nur Izzah Farhana Mohamad Azhar
Olivier Lefebvre
Peter S Zammit
Anne-Gaëlle Borycki
author_sort Shantisree Sandeepani Rayagiri
title Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal
title_short Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal
title_full Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal
title_fullStr Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal
title_full_unstemmed Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal
title_sort basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/769c8e79a91d443abc08b2d2575d38d8
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