TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling

TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling

Tetraspanin 8 (TSPAN8) has been implicated in a number of different tumours, but the underlying mechanisms remain unclear. Here, in breast cancer the authors highlight a role for TSPAN8 in promoting tumorigenesis through the activation of Hedgehog signalling.

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Detalles Bibliográficos
Autores principales: Rongxuan Zhu, Olivier Gires, Liqun Zhu, Jun Liu, Junjian Li, Hao Yang, Gaoda Ju, Jing Huang, Weiyu Ge, Yi Chen, Zhimin Lu, Hongxia Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
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Acceso en línea:https://doaj.org/article/769dc01c63c3489aa39054afc3be9b52
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