Inhibition of histone deacetylase activity in human endometrial stromal cells promotes extracellular matrix remodelling and limits embryo invasion.
Invasion of the trophoblast into the maternal decidua is regulated by both the trophoectoderm and the endometrial stroma, and entails the action of tissue remodeling enzymes. Trophoblast invasion requires the action of metalloproteinases (MMPs) to degrade extracellular matrix (ECM) proteins and in t...
Enregistré dans:
Auteurs principaux: | Carlos Estella, Isabel Herrer, Stuart P Atkinson, Alicia Quiñonero, Sebastián Martínez, Antonio Pellicer, Carlos Simón |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/76aa47bcd3c54bf8a73d7d42d92c2242 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
miRNA signature and Dicer requirement during human endometrial stromal decidualization in vitro.
par: Carlos Estella, et autres
Publié: (2012) -
Histone Deacetylase Inhibitors: A Promising Therapeutic Alternative for Endometrial Carcinoma
par: Iason Psilopatis, et autres
Publié: (2021) -
Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
par: Yang Hai, et autres
Publié: (2017) -
The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation
par: Bruno Mugat, et autres
Publié: (2020) -
Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation
par: Valentina Poli, et autres
Publié: (2021)