Point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge

Implant infection is the most common mode of joint replacement failure with serious complications. Here, the authors report on the in vivo application of a prophylactic coating technology that can incorporate a range of antibiotics and be applied in the operating room prior to implantation.

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Autores principales: Weixian Xi, Vishal Hegde, Stephen D. Zoller, Howard Y. Park, Christopher M. Hart, Takeru Kondo, Christopher D. Hamad, Yan Hu, Amanda H. Loftin, Daniel O. Johansen, Zachary Burke, Samuel Clarkson, Chad Ishmael, Kellyn Hori, Zeinab Mamouei, Hiroko Okawa, Ichiro Nishimura, Nicholas M. Bernthal, Tatiana Segura
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/76aa4dbb4edd442f94aaa3e0f4b4b488
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spelling oai:doaj.org-article:76aa4dbb4edd442f94aaa3e0f4b4b4882021-12-02T17:24:12ZPoint-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge10.1038/s41467-021-25383-z2041-1723https://doaj.org/article/76aa4dbb4edd442f94aaa3e0f4b4b4882021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25383-zhttps://doaj.org/toc/2041-1723Implant infection is the most common mode of joint replacement failure with serious complications. Here, the authors report on the in vivo application of a prophylactic coating technology that can incorporate a range of antibiotics and be applied in the operating room prior to implantation.Weixian XiVishal HegdeStephen D. ZollerHoward Y. ParkChristopher M. HartTakeru KondoChristopher D. HamadYan HuAmanda H. LoftinDaniel O. JohansenZachary BurkeSamuel ClarksonChad IshmaelKellyn HoriZeinab MamoueiHiroko OkawaIchiro NishimuraNicholas M. BernthalTatiana SeguraNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Weixian Xi
Vishal Hegde
Stephen D. Zoller
Howard Y. Park
Christopher M. Hart
Takeru Kondo
Christopher D. Hamad
Yan Hu
Amanda H. Loftin
Daniel O. Johansen
Zachary Burke
Samuel Clarkson
Chad Ishmael
Kellyn Hori
Zeinab Mamouei
Hiroko Okawa
Ichiro Nishimura
Nicholas M. Bernthal
Tatiana Segura
Point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge
description Implant infection is the most common mode of joint replacement failure with serious complications. Here, the authors report on the in vivo application of a prophylactic coating technology that can incorporate a range of antibiotics and be applied in the operating room prior to implantation.
format article
author Weixian Xi
Vishal Hegde
Stephen D. Zoller
Howard Y. Park
Christopher M. Hart
Takeru Kondo
Christopher D. Hamad
Yan Hu
Amanda H. Loftin
Daniel O. Johansen
Zachary Burke
Samuel Clarkson
Chad Ishmael
Kellyn Hori
Zeinab Mamouei
Hiroko Okawa
Ichiro Nishimura
Nicholas M. Bernthal
Tatiana Segura
author_facet Weixian Xi
Vishal Hegde
Stephen D. Zoller
Howard Y. Park
Christopher M. Hart
Takeru Kondo
Christopher D. Hamad
Yan Hu
Amanda H. Loftin
Daniel O. Johansen
Zachary Burke
Samuel Clarkson
Chad Ishmael
Kellyn Hori
Zeinab Mamouei
Hiroko Okawa
Ichiro Nishimura
Nicholas M. Bernthal
Tatiana Segura
author_sort Weixian Xi
title Point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge
title_short Point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge
title_full Point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge
title_fullStr Point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge
title_full_unstemmed Point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge
title_sort point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/76aa4dbb4edd442f94aaa3e0f4b4b488
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