Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons

In neurons, brain-derived neurotrophic factor (BDNF) transcription is activated by synaptic activity, in part by epigenetic regulation of its promoter regions. Here the authors characterize histone modifications in response to NMDA treatment that result in different kinetics of Bdnf activation from...

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Autores principales:	Ernest Palomer, Javier Carretero, Stefano Benvegnù, Carlos G. Dotti, Mauricio G. Martin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/76abe5f97a35480083f5247a8ddfdb84
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spelling	oai:doaj.org-article:76abe5f97a35480083f5247a8ddfdb842021-12-02T14:39:52ZNeuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons10.1038/ncomms110812041-1723https://doaj.org/article/76abe5f97a35480083f5247a8ddfdb842016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11081https://doaj.org/toc/2041-1723In neurons, brain-derived neurotrophic factor (BDNF) transcription is activated by synaptic activity, in part by epigenetic regulation of its promoter regions. Here the authors characterize histone modifications in response to NMDA treatment that result in different kinetics of Bdnf activation from its different promoter regions.Ernest PalomerJavier CarreteroStefano BenvegnùCarlos G. DottiMauricio G. MartinNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ernest Palomer Javier Carretero Stefano Benvegnù Carlos G. Dotti Mauricio G. Martin Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons
description	In neurons, brain-derived neurotrophic factor (BDNF) transcription is activated by synaptic activity, in part by epigenetic regulation of its promoter regions. Here the authors characterize histone modifications in response to NMDA treatment that result in different kinetics of Bdnf activation from its different promoter regions.
format	article
author	Ernest Palomer Javier Carretero Stefano Benvegnù Carlos G. Dotti Mauricio G. Martin
author_facet	Ernest Palomer Javier Carretero Stefano Benvegnù Carlos G. Dotti Mauricio G. Martin
author_sort	Ernest Palomer
title	Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons
title_short	Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons
title_full	Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons
title_fullStr	Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons
title_full_unstemmed	Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons
title_sort	neuronal activity controls bdnf expression via polycomb de-repression and creb/cbp/jmjd3 activation in mature neurons
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/76abe5f97a35480083f5247a8ddfdb84
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Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons

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