Comparative analysis of tuberous root metabolites between cultivated and wild varieties of Rehmannia glutinosa by widely targeted metabolomics

Abstract Differential metabolites between tuberous roots from cultivated variety (ZP) and wild variety (YS) of Rehmannia glutinosa were analyzed by widely targeted metabolomics, and annotated to KEGG pathways. 228 secondary metabolites (SM) in ZP and YS were detected, of which 58 were differential m...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yanqing Zhou, Luying Shao, Jialin Zhu, Huimin Li, Hongying Duan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/76b0d6ef0c934dd5b0695b131f0754e0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:76b0d6ef0c934dd5b0695b131f0754e0
record_format	dspace
spelling	oai:doaj.org-article:76b0d6ef0c934dd5b0695b131f0754e02021-12-02T18:25:04ZComparative analysis of tuberous root metabolites between cultivated and wild varieties of Rehmannia glutinosa by widely targeted metabolomics10.1038/s41598-021-90961-62045-2322https://doaj.org/article/76b0d6ef0c934dd5b0695b131f0754e02021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-90961-6https://doaj.org/toc/2045-2322Abstract Differential metabolites between tuberous roots from cultivated variety (ZP) and wild variety (YS) of Rehmannia glutinosa were analyzed by widely targeted metabolomics, and annotated to KEGG pathways. 228 secondary metabolites (SM) in ZP and YS were detected, of which 58 were differential metabolites (DM), including 41 flavonoids, 10 phenolic acids, 3 terpenoids, 2 alkaloids and 2 others, and 170 were unchanged; Among 58 DMs, 44 (75.9%) were up-regulated in YS, of which 30 were unique to YS, while 14 (24.1%) were down-regulated in YS, of which 10 were unique to ZP; Among flavonoids, 33 (80.5%) were more highly expressed in YS than in ZP; Among phenolic acids, 7 (70%) were more highly expressed in YS than in ZP; 12 of 58 DMs were annotated into 17 types of KEGG pathways. Among them, benzoic acid and p-Coumaryl alcohol were up-regulated in YS, and annotated into 10 pathways (58.8%) and 4 pathways (23.5%), respectively. In addition, much of DMs possess various pharmacological effects. These results indicated better quality of YS than ZP and the necessity of YS domestication. Taken together, this study will provide a reference for the scientific introduction, comprehensive development and utilization of wild Rehmannia glutinosa.Yanqing ZhouLuying ShaoJialin ZhuHuimin LiHongying DuanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yanqing Zhou Luying Shao Jialin Zhu Huimin Li Hongying Duan Comparative analysis of tuberous root metabolites between cultivated and wild varieties of Rehmannia glutinosa by widely targeted metabolomics
description	Abstract Differential metabolites between tuberous roots from cultivated variety (ZP) and wild variety (YS) of Rehmannia glutinosa were analyzed by widely targeted metabolomics, and annotated to KEGG pathways. 228 secondary metabolites (SM) in ZP and YS were detected, of which 58 were differential metabolites (DM), including 41 flavonoids, 10 phenolic acids, 3 terpenoids, 2 alkaloids and 2 others, and 170 were unchanged; Among 58 DMs, 44 (75.9%) were up-regulated in YS, of which 30 were unique to YS, while 14 (24.1%) were down-regulated in YS, of which 10 were unique to ZP; Among flavonoids, 33 (80.5%) were more highly expressed in YS than in ZP; Among phenolic acids, 7 (70%) were more highly expressed in YS than in ZP; 12 of 58 DMs were annotated into 17 types of KEGG pathways. Among them, benzoic acid and p-Coumaryl alcohol were up-regulated in YS, and annotated into 10 pathways (58.8%) and 4 pathways (23.5%), respectively. In addition, much of DMs possess various pharmacological effects. These results indicated better quality of YS than ZP and the necessity of YS domestication. Taken together, this study will provide a reference for the scientific introduction, comprehensive development and utilization of wild Rehmannia glutinosa.
format	article
author	Yanqing Zhou Luying Shao Jialin Zhu Huimin Li Hongying Duan
author_facet	Yanqing Zhou Luying Shao Jialin Zhu Huimin Li Hongying Duan
author_sort	Yanqing Zhou
title	Comparative analysis of tuberous root metabolites between cultivated and wild varieties of Rehmannia glutinosa by widely targeted metabolomics
title_short	Comparative analysis of tuberous root metabolites between cultivated and wild varieties of Rehmannia glutinosa by widely targeted metabolomics
title_full	Comparative analysis of tuberous root metabolites between cultivated and wild varieties of Rehmannia glutinosa by widely targeted metabolomics
title_fullStr	Comparative analysis of tuberous root metabolites between cultivated and wild varieties of Rehmannia glutinosa by widely targeted metabolomics
title_full_unstemmed	Comparative analysis of tuberous root metabolites between cultivated and wild varieties of Rehmannia glutinosa by widely targeted metabolomics
title_sort	comparative analysis of tuberous root metabolites between cultivated and wild varieties of rehmannia glutinosa by widely targeted metabolomics
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/76b0d6ef0c934dd5b0695b131f0754e0
work_keys_str_mv	AT yanqingzhou comparativeanalysisoftuberousrootmetabolitesbetweencultivatedandwildvarietiesofrehmanniaglutinosabywidelytargetedmetabolomics AT luyingshao comparativeanalysisoftuberousrootmetabolitesbetweencultivatedandwildvarietiesofrehmanniaglutinosabywidelytargetedmetabolomics AT jialinzhu comparativeanalysisoftuberousrootmetabolitesbetweencultivatedandwildvarietiesofrehmanniaglutinosabywidelytargetedmetabolomics AT huiminli comparativeanalysisoftuberousrootmetabolitesbetweencultivatedandwildvarietiesofrehmanniaglutinosabywidelytargetedmetabolomics AT hongyingduan comparativeanalysisoftuberousrootmetabolitesbetweencultivatedandwildvarietiesofrehmanniaglutinosabywidelytargetedmetabolomics
_version_	1718378045605150720

Comparative analysis of tuberous root metabolites between cultivated and wild varieties of Rehmannia glutinosa by widely targeted metabolomics

Ejemplares similares