On pathogenesis of arterial hypertension in type 2 diabetes mellitus

Aim. To study the functional state of arterioles in patients with type 2 diabetes mellitus and concomitant arterial hypertension (AH) and evaluatethe role of sodium in mechanisms of elevation of arterial pressure (AP) in this pathology. Materials and methods. 163 patients of whom 83 had DM2 with A...

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Autores principales: Violen Stepanovich Volkov, Evgenia Vladimirovna Rudenko, Svetlana Anatol'evna Rokkina, Olga Borisovna Poselyugina
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RU
Publicado: Endocrinology Research Centre 2011
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spelling oai:doaj.org-article:76b85d76e14946808342491ddf700db82021-11-14T09:00:16ZOn pathogenesis of arterial hypertension in type 2 diabetes mellitus2072-03512072-037810.14341/2072-0351-5635https://doaj.org/article/76b85d76e14946808342491ddf700db82011-06-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5635https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To study the functional state of arterioles in patients with type 2 diabetes mellitus and concomitant arterial hypertension (AH) and evaluatethe role of sodium in mechanisms of elevation of arterial pressure (AP) in this pathology. Materials and methods. 163 patients of whom 83 had DM2 with AH and 80 essential hypertension. They were examined by dopplerography of themicrocirclatory bed, measurement of arterial blood flow and daily sodium urinary excretion. Results. Patients with essential AH showed increased arteriolar circulation rate and enhanced reactivity of microvessels. These parameters werereduced in patients with DM2 and AH who consumed large amount of table salt. Conclusion. Mechanisms of development of essential AH and AH in DM2 are significantly different.Violen Stepanovich VolkovEvgenia Vladimirovna RudenkoSvetlana Anatol'evna RokkinaOlga Borisovna PoselyuginaEndocrinology Research Centrearticlearterial hypertensiontype 2 diabeteslinear blood flow velocityNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 14, Iss 2, Pp 53-55 (2011)
institution DOAJ
collection DOAJ
language EN
RU
topic arterial hypertension
type 2 diabetes
linear blood flow velocity
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle arterial hypertension
type 2 diabetes
linear blood flow velocity
Nutritional diseases. Deficiency diseases
RC620-627
Violen Stepanovich Volkov
Evgenia Vladimirovna Rudenko
Svetlana Anatol'evna Rokkina
Olga Borisovna Poselyugina
On pathogenesis of arterial hypertension in type 2 diabetes mellitus
description Aim. To study the functional state of arterioles in patients with type 2 diabetes mellitus and concomitant arterial hypertension (AH) and evaluatethe role of sodium in mechanisms of elevation of arterial pressure (AP) in this pathology. Materials and methods. 163 patients of whom 83 had DM2 with AH and 80 essential hypertension. They were examined by dopplerography of themicrocirclatory bed, measurement of arterial blood flow and daily sodium urinary excretion. Results. Patients with essential AH showed increased arteriolar circulation rate and enhanced reactivity of microvessels. These parameters werereduced in patients with DM2 and AH who consumed large amount of table salt. Conclusion. Mechanisms of development of essential AH and AH in DM2 are significantly different.
format article
author Violen Stepanovich Volkov
Evgenia Vladimirovna Rudenko
Svetlana Anatol'evna Rokkina
Olga Borisovna Poselyugina
author_facet Violen Stepanovich Volkov
Evgenia Vladimirovna Rudenko
Svetlana Anatol'evna Rokkina
Olga Borisovna Poselyugina
author_sort Violen Stepanovich Volkov
title On pathogenesis of arterial hypertension in type 2 diabetes mellitus
title_short On pathogenesis of arterial hypertension in type 2 diabetes mellitus
title_full On pathogenesis of arterial hypertension in type 2 diabetes mellitus
title_fullStr On pathogenesis of arterial hypertension in type 2 diabetes mellitus
title_full_unstemmed On pathogenesis of arterial hypertension in type 2 diabetes mellitus
title_sort on pathogenesis of arterial hypertension in type 2 diabetes mellitus
publisher Endocrinology Research Centre
publishDate 2011
url https://doaj.org/article/76b85d76e14946808342491ddf700db8
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AT svetlanaanatolevnarokkina onpathogenesisofarterialhypertensionintype2diabetesmellitus
AT olgaborisovnaposelyugina onpathogenesisofarterialhypertensionintype2diabetesmellitus
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