Mutational status of plasma exosomal KRAS predicts outcome in patients with metastatic colorectal cancer

Mutational status of plasma exosomal KRAS predicts outcome in patients with metastatic colorectal cancer

Abstract Liquid biopsy has become a useful alternative in metastatic colorectal cancer (mCRC) patients when tissue biopsy of metastatic sites is not feasible. In this study we aimed to investigate the clinical utility of circulating exosomes DNA in the management of mCRC patients. Exosomes level and...

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Autores principales: Donatella Lucchetti, Ina Valeria Zurlo, Filomena Colella, Claudio Ricciardi-Tenore, Mariantonietta Di Salvatore, Giampaolo Tortora, Ruggero De Maria, Felice Giuliante, Alessandra Cassano, Michele Basso, Antonio Crucitti, Ilaria Laurenzana, Giulia Artemi, Alessandro Sgambato
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/76b8a6a6c9ab48f3a5d635c255f279da
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https://doaj.org/article/76b8a6a6c9ab48f3a5d635c255f279da

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