Mutational status of plasma exosomal KRAS predicts outcome in patients with metastatic colorectal cancer
Abstract Liquid biopsy has become a useful alternative in metastatic colorectal cancer (mCRC) patients when tissue biopsy of metastatic sites is not feasible. In this study we aimed to investigate the clinical utility of circulating exosomes DNA in the management of mCRC patients. Exosomes level and...
Saved in:
Main Authors: | Donatella Lucchetti, Ina Valeria Zurlo, Filomena Colella, Claudio Ricciardi-Tenore, Mariantonietta Di Salvatore, Giampaolo Tortora, Ruggero De Maria, Felice Giuliante, Alessandra Cassano, Michele Basso, Antonio Crucitti, Ilaria Laurenzana, Giulia Artemi, Alessandro Sgambato |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/76b8a6a6c9ab48f3a5d635c255f279da |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A potent KRAS macromolecule degrader specifically targeting tumours with mutant KRAS
by: Nicolas Bery, et al.
Published: (2020) -
Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK
by: Jieqiong Wang, et al.
Published: (2016) -
Oncogenic KRAS: Signaling and Drug Resistance
by: Hyeon Jin Kim, et al.
Published: (2021) -
Two Novel Precursors of the HIV-1 Protease Inhibitor Darunavir Target the UPR/Proteasome System in Human Hepatocellular Carcinoma Cell Line HepG2
by: Roberta Rinaldi, et al.
Published: (2021) -
Immune modulatory effects of oncogenic KRAS in cancer
by: Shaima’a Hamarsheh, et al.
Published: (2020)