A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995).

<h4>Background</h4>Shigella dysenteriae type 1 (Sd1) is a cause of major dysentery outbreaks, particularly among children and displaced populations in tropical countries. Although outbreaks continue, the characteristics of such outbreaks have rarely been documented. Here, we describe the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Solen Kernéis, Philippe J Guerin, Lorenz von Seidlein, Dominique Legros, Rebecca F Grais
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
Materias:
R
Q
Acceso en línea:https://doaj.org/article/76d3e5c8da1b4b2fbf5604dedb9df3e2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:76d3e5c8da1b4b2fbf5604dedb9df3e2
record_format dspace
spelling oai:doaj.org-article:76d3e5c8da1b4b2fbf5604dedb9df3e22021-11-25T06:17:19ZA look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995).1932-620310.1371/journal.pone.0004494https://doaj.org/article/76d3e5c8da1b4b2fbf5604dedb9df3e22009-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19214226/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Shigella dysenteriae type 1 (Sd1) is a cause of major dysentery outbreaks, particularly among children and displaced populations in tropical countries. Although outbreaks continue, the characteristics of such outbreaks have rarely been documented. Here, we describe the Sd1 outbreaks occurring between 1993 and 1995 in 11 refugee settlements in Rwanda, Tanzania and Democratic Republic of the Congo (DRC). We also explored the links between the different types of the camps and the magnitude of the outbreaks.<h4>Methodology/principal findings</h4>Number of cases of bloody diarrhea and deaths were collected on a weekly basis in 11 refugee camps, and analyzed retrospectively. Between November 1993 and February 1995, 181,921 cases of bloody diarrhea were reported. Attack rates ranged from 6.3% to 39.1% and case fatality ratios (CFRs) from 1.5% to 9.0% (available for 5 camps). The CFRs were higher in children under age 5. In Tanzania where the response was rapidly deployed, the mean attack rate was lower than in camps in the region of Goma without an immediate response (13.3% versus 32.1% respectively).<h4>Conclusions/significance</h4>This description, and the areas where data is missing, highlight both the importance of collecting data in future epidemics, difficulties in documenting outbreaks occurring in complex emergencies and most importantly, the need to assure that minimal requirements are met.Solen KernéisPhilippe J GuerinLorenz von SeidleinDominique LegrosRebecca F GraisPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 4, Iss 2, p e4494 (2009)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Solen Kernéis
Philippe J Guerin
Lorenz von Seidlein
Dominique Legros
Rebecca F Grais
A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995).
description <h4>Background</h4>Shigella dysenteriae type 1 (Sd1) is a cause of major dysentery outbreaks, particularly among children and displaced populations in tropical countries. Although outbreaks continue, the characteristics of such outbreaks have rarely been documented. Here, we describe the Sd1 outbreaks occurring between 1993 and 1995 in 11 refugee settlements in Rwanda, Tanzania and Democratic Republic of the Congo (DRC). We also explored the links between the different types of the camps and the magnitude of the outbreaks.<h4>Methodology/principal findings</h4>Number of cases of bloody diarrhea and deaths were collected on a weekly basis in 11 refugee camps, and analyzed retrospectively. Between November 1993 and February 1995, 181,921 cases of bloody diarrhea were reported. Attack rates ranged from 6.3% to 39.1% and case fatality ratios (CFRs) from 1.5% to 9.0% (available for 5 camps). The CFRs were higher in children under age 5. In Tanzania where the response was rapidly deployed, the mean attack rate was lower than in camps in the region of Goma without an immediate response (13.3% versus 32.1% respectively).<h4>Conclusions/significance</h4>This description, and the areas where data is missing, highlight both the importance of collecting data in future epidemics, difficulties in documenting outbreaks occurring in complex emergencies and most importantly, the need to assure that minimal requirements are met.
format article
author Solen Kernéis
Philippe J Guerin
Lorenz von Seidlein
Dominique Legros
Rebecca F Grais
author_facet Solen Kernéis
Philippe J Guerin
Lorenz von Seidlein
Dominique Legros
Rebecca F Grais
author_sort Solen Kernéis
title A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995).
title_short A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995).
title_full A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995).
title_fullStr A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995).
title_full_unstemmed A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995).
title_sort look back at an ongoing problem: shigella dysenteriae type 1 epidemics in refugee settings in central africa (1993-1995).
publisher Public Library of Science (PLoS)
publishDate 2009
url https://doaj.org/article/76d3e5c8da1b4b2fbf5604dedb9df3e2
work_keys_str_mv AT solenkerneis alookbackatanongoingproblemshigelladysenteriaetype1epidemicsinrefugeesettingsincentralafrica19931995
AT philippejguerin alookbackatanongoingproblemshigelladysenteriaetype1epidemicsinrefugeesettingsincentralafrica19931995
AT lorenzvonseidlein alookbackatanongoingproblemshigelladysenteriaetype1epidemicsinrefugeesettingsincentralafrica19931995
AT dominiquelegros alookbackatanongoingproblemshigelladysenteriaetype1epidemicsinrefugeesettingsincentralafrica19931995
AT rebeccafgrais alookbackatanongoingproblemshigelladysenteriaetype1epidemicsinrefugeesettingsincentralafrica19931995
AT solenkerneis lookbackatanongoingproblemshigelladysenteriaetype1epidemicsinrefugeesettingsincentralafrica19931995
AT philippejguerin lookbackatanongoingproblemshigelladysenteriaetype1epidemicsinrefugeesettingsincentralafrica19931995
AT lorenzvonseidlein lookbackatanongoingproblemshigelladysenteriaetype1epidemicsinrefugeesettingsincentralafrica19931995
AT dominiquelegros lookbackatanongoingproblemshigelladysenteriaetype1epidemicsinrefugeesettingsincentralafrica19931995
AT rebeccafgrais lookbackatanongoingproblemshigelladysenteriaetype1epidemicsinrefugeesettingsincentralafrica19931995
_version_ 1718413991108149248