Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture

Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture

RNA interactome capture allows the detailed investigation of RNA-bound proteomes. Here the authors describe enhanced RNA-interactome capture using LNA-modified probes for increased sensitivity and specificity.

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Bibliographic Details
Main Authors: Joel I. Perez-Perri, Birgit Rogell, Thomas Schwarzl, Frank Stein, Yang Zhou, Mandy Rettel, Annika Brosig, Matthias W. Hentze
Format: article
Language:EN
Published: Nature Portfolio 2018
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Science
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Online Access:https://doaj.org/article/76eaf12d527848aa9f4fbd5d49b9c9e2
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Summary:RNA interactome capture allows the detailed investigation of RNA-bound proteomes. Here the authors describe enhanced RNA-interactome capture using LNA-modified probes for increased sensitivity and specificity.

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