Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture

RNA interactome capture allows the detailed investigation of RNA-bound proteomes. Here the authors describe enhanced RNA-interactome capture using LNA-modified probes for increased sensitivity and specificity.

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Auteurs principaux: Joel I. Perez-Perri, Birgit Rogell, Thomas Schwarzl, Frank Stein, Yang Zhou, Mandy Rettel, Annika Brosig, Matthias W. Hentze
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/76eaf12d527848aa9f4fbd5d49b9c9e2
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spelling oai:doaj.org-article:76eaf12d527848aa9f4fbd5d49b9c9e22021-12-02T16:56:59ZDiscovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture10.1038/s41467-018-06557-82041-1723https://doaj.org/article/76eaf12d527848aa9f4fbd5d49b9c9e22018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06557-8https://doaj.org/toc/2041-1723RNA interactome capture allows the detailed investigation of RNA-bound proteomes. Here the authors describe enhanced RNA-interactome capture using LNA-modified probes for increased sensitivity and specificity.Joel I. Perez-PerriBirgit RogellThomas SchwarzlFrank SteinYang ZhouMandy RettelAnnika BrosigMatthias W. HentzeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Joel I. Perez-Perri
Birgit Rogell
Thomas Schwarzl
Frank Stein
Yang Zhou
Mandy Rettel
Annika Brosig
Matthias W. Hentze
Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture
description RNA interactome capture allows the detailed investigation of RNA-bound proteomes. Here the authors describe enhanced RNA-interactome capture using LNA-modified probes for increased sensitivity and specificity.
format article
author Joel I. Perez-Perri
Birgit Rogell
Thomas Schwarzl
Frank Stein
Yang Zhou
Mandy Rettel
Annika Brosig
Matthias W. Hentze
author_facet Joel I. Perez-Perri
Birgit Rogell
Thomas Schwarzl
Frank Stein
Yang Zhou
Mandy Rettel
Annika Brosig
Matthias W. Hentze
author_sort Joel I. Perez-Perri
title Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture
title_short Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture
title_full Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture
title_fullStr Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture
title_full_unstemmed Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture
title_sort discovery of rna-binding proteins and characterization of their dynamic responses by enhanced rna interactome capture
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/76eaf12d527848aa9f4fbd5d49b9c9e2
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