Suppressor effect of catechol-O-methyltransferase gene in prostate cancer.

Catechol-estrogens can cause genetic mutations and to counteract their oncogenicity, the catechol-O-methyltransferase (COMT) gene is capable of neutralizing these reactive compounds. In this study, we determined the functional effects and regulation of COMT in prostate cancer. Both the Cancer Genome...

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Auteurs principaux: Yutaka Hashimoto, Marisa Shiina, Shigekatsu Maekawa, Taku Kato, Varahram Shahryari, Priyanka Kulkarni, Pritha Dasgupta, Soichiro Yamamura, Sharanjot Saini, Z Laura Tabatabai, Rajvir Dahiya, Yuichiro Tanaka
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/76ee1a5071504b8785c7c337d3e5510a
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