Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy
Brain tumours are associated with epilepsy. Here the authors show, using a mouse model, that the degradation of perineuronal nets around fast spiking interneurons near the tumour contribute to seizures by increasing their membrane capacitance and firing.
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| Main Authors: | , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
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| Subjects: | |
| Online Access: | https://doaj.org/article/76ee429c0d5743bdbdf32e9dfbd740e1 |
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