COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS
The article considers variability of antigen protein E of different tick-borne encephalitis (TBE) strains at the level of physicochemical properties of amino acid residues. The authors evaluated variety of properties of protein amino acids involved in antigen-antibody interaction. 180 variants of TB...
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Scientific Сentre for Family Health and Human Reproduction Problems
2014
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oai:doaj.org-article:7709164f6af243f6bd74489a129d28252021-11-23T06:14:31ZCOMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS2541-94202587-9596https://doaj.org/article/7709164f6af243f6bd74489a129d28252014-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1843https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The article considers variability of antigen protein E of different tick-borne encephalitis (TBE) strains at the level of physicochemical properties of amino acid residues. The authors evaluated variety of properties of protein amino acids involved in antigen-antibody interaction. 180 variants of TBEVE protein in database NCB1 were detected, differing in physical and chemical properties of amino acid residues. This implies that natural variants of TBEV strains can potentially be detected, that escaped from the immune response induced by standard vaccine.Yu. S. BukinYu. P. DzhioevI. V. KozlovaD. .. RuzekV. I. ZlobinScientific Сentre for Family Health and Human Reproduction Problemsarticletick-borne encephalitis virusenvelope protein etbe vaccineproteomicScienceQRUActa Biomedica Scientifica, Vol 0, Iss 6, Pp 84-88 (2014) |
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DOAJ |
language |
RU |
topic |
tick-borne encephalitis virus envelope protein e tbe vaccine proteomic Science Q |
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tick-borne encephalitis virus envelope protein e tbe vaccine proteomic Science Q Yu. S. Bukin Yu. P. Dzhioev I. V. Kozlova D. .. Ruzek V. I. Zlobin COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS |
description |
The article considers variability of antigen protein E of different tick-borne encephalitis (TBE) strains at the level of physicochemical properties of amino acid residues. The authors evaluated variety of properties of protein amino acids involved in antigen-antibody interaction. 180 variants of TBEVE protein in database NCB1 were detected, differing in physical and chemical properties of amino acid residues. This implies that natural variants of TBEV strains can potentially be detected, that escaped from the immune response induced by standard vaccine. |
format |
article |
author |
Yu. S. Bukin Yu. P. Dzhioev I. V. Kozlova D. .. Ruzek V. I. Zlobin |
author_facet |
Yu. S. Bukin Yu. P. Dzhioev I. V. Kozlova D. .. Ruzek V. I. Zlobin |
author_sort |
Yu. S. Bukin |
title |
COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS |
title_short |
COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS |
title_full |
COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS |
title_fullStr |
COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS |
title_full_unstemmed |
COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS |
title_sort |
comparative analysis of the physicochemical properties of amino acid residues within the various embodiments of the envelope protein e tick-borne encephalitis virus |
publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
publishDate |
2014 |
url |
https://doaj.org/article/7709164f6af243f6bd74489a129d2825 |
work_keys_str_mv |
AT yusbukin comparativeanalysisofthephysicochemicalpropertiesofaminoacidresidueswithinthevariousembodimentsoftheenvelopeproteinetickborneencephalitisvirus AT yupdzhioev comparativeanalysisofthephysicochemicalpropertiesofaminoacidresidueswithinthevariousembodimentsoftheenvelopeproteinetickborneencephalitisvirus AT ivkozlova comparativeanalysisofthephysicochemicalpropertiesofaminoacidresidueswithinthevariousembodimentsoftheenvelopeproteinetickborneencephalitisvirus AT druzek comparativeanalysisofthephysicochemicalpropertiesofaminoacidresidueswithinthevariousembodimentsoftheenvelopeproteinetickborneencephalitisvirus AT vizlobin comparativeanalysisofthephysicochemicalpropertiesofaminoacidresidueswithinthevariousembodimentsoftheenvelopeproteinetickborneencephalitisvirus |
_version_ |
1718417076467531776 |