Mechanism of peripheral nerve modulation and recent applications
Neuromodulation is a multi-interdisciplinary field of neuroscience, neural engineering, and medicine in a complex, but a way of understanding. Recently, the interest and researches in this field have been attracted due to its promising applications such as bionic limbs and bioelectronic medicine. Fo...
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2021
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oai:doaj.org-article:770d49ba37e646798969d9c49c9373cd2021-11-26T11:19:47ZMechanism of peripheral nerve modulation and recent applications1559-96121559-962010.1080/15599612.2021.1978601https://doaj.org/article/770d49ba37e646798969d9c49c9373cd2021-01-01T00:00:00Zhttp://dx.doi.org/10.1080/15599612.2021.1978601https://doaj.org/toc/1559-9612https://doaj.org/toc/1559-9620Neuromodulation is a multi-interdisciplinary field of neuroscience, neural engineering, and medicine in a complex, but a way of understanding. Recently, the interest and researches in this field have been attracted due to its promising applications such as bionic limbs and bioelectronic medicine. For easier entry into this field, in this review, we approach the basic mechanism, methods, and applications of peripheral neuromodulation sequentially. Firstly, the overall structure and functions of the human nervous system are introduced, especially in the peripheral nervous system (PNS). Specifically, the fundamental neurophysiology regarding action potentials and neural signals is introduced to understand the communication between the neurons. Thereafter, two main methods for peripheral neuromodulation, which are electrical and optogenetic approaches, are introduced with the principles of the state-of-art devices. Finally, advanced applications of neuromodulation combined with the sensor, stimulator, and controller, called a closed-loop system are introduced with an example of bionic limbs.Heejae ShinMinseok KangSanghoon LeeTaylor & Francis Grouparticleneuromodulationperipheral nerveelectrical stimulationoptogeneticsbioelectronic medicinebionic limbMaterials of engineering and construction. Mechanics of materialsTA401-492Applied optics. PhotonicsTA1501-1820ENInternational Journal of Optomechatronics, Vol 15, Iss 1, Pp 182-198 (2021) |
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DOAJ |
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neuromodulation peripheral nerve electrical stimulation optogenetics bioelectronic medicine bionic limb Materials of engineering and construction. Mechanics of materials TA401-492 Applied optics. Photonics TA1501-1820 |
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neuromodulation peripheral nerve electrical stimulation optogenetics bioelectronic medicine bionic limb Materials of engineering and construction. Mechanics of materials TA401-492 Applied optics. Photonics TA1501-1820 Heejae Shin Minseok Kang Sanghoon Lee Mechanism of peripheral nerve modulation and recent applications |
description |
Neuromodulation is a multi-interdisciplinary field of neuroscience, neural engineering, and medicine in a complex, but a way of understanding. Recently, the interest and researches in this field have been attracted due to its promising applications such as bionic limbs and bioelectronic medicine. For easier entry into this field, in this review, we approach the basic mechanism, methods, and applications of peripheral neuromodulation sequentially. Firstly, the overall structure and functions of the human nervous system are introduced, especially in the peripheral nervous system (PNS). Specifically, the fundamental neurophysiology regarding action potentials and neural signals is introduced to understand the communication between the neurons. Thereafter, two main methods for peripheral neuromodulation, which are electrical and optogenetic approaches, are introduced with the principles of the state-of-art devices. Finally, advanced applications of neuromodulation combined with the sensor, stimulator, and controller, called a closed-loop system are introduced with an example of bionic limbs. |
format |
article |
author |
Heejae Shin Minseok Kang Sanghoon Lee |
author_facet |
Heejae Shin Minseok Kang Sanghoon Lee |
author_sort |
Heejae Shin |
title |
Mechanism of peripheral nerve modulation and recent applications |
title_short |
Mechanism of peripheral nerve modulation and recent applications |
title_full |
Mechanism of peripheral nerve modulation and recent applications |
title_fullStr |
Mechanism of peripheral nerve modulation and recent applications |
title_full_unstemmed |
Mechanism of peripheral nerve modulation and recent applications |
title_sort |
mechanism of peripheral nerve modulation and recent applications |
publisher |
Taylor & Francis Group |
publishDate |
2021 |
url |
https://doaj.org/article/770d49ba37e646798969d9c49c9373cd |
work_keys_str_mv |
AT heejaeshin mechanismofperipheralnervemodulationandrecentapplications AT minseokkang mechanismofperipheralnervemodulationandrecentapplications AT sanghoonlee mechanismofperipheralnervemodulationandrecentapplications |
_version_ |
1718409542196264960 |