Structure of a MacAB-like efflux pump from Streptococcus pneumoniae

Bacterial ATP-binding cassette (ABC)-type efflux pumps are involved in the resistance of antibiotics and antimicrobial peptides. Here authors report the crystal structures and ATPase activity of the MacAB-like efflux pump from Streptococcus pneumonia and describe a putative substrate transport mecha...

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Autores principales: Hong-Bo Yang, Wen-Tao Hou, Meng-Ting Cheng, Yong-Liang Jiang, Yuxing Chen, Cong-Zhao Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/771197c9eb5a453db314d079cce6a0ba
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spelling oai:doaj.org-article:771197c9eb5a453db314d079cce6a0ba2021-12-02T15:33:37ZStructure of a MacAB-like efflux pump from Streptococcus pneumoniae10.1038/s41467-017-02741-42041-1723https://doaj.org/article/771197c9eb5a453db314d079cce6a0ba2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02741-4https://doaj.org/toc/2041-1723Bacterial ATP-binding cassette (ABC)-type efflux pumps are involved in the resistance of antibiotics and antimicrobial peptides. Here authors report the crystal structures and ATPase activity of the MacAB-like efflux pump from Streptococcus pneumonia and describe a putative substrate transport mechanism.Hong-Bo YangWen-Tao HouMeng-Ting ChengYong-Liang JiangYuxing ChenCong-Zhao ZhouNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hong-Bo Yang
Wen-Tao Hou
Meng-Ting Cheng
Yong-Liang Jiang
Yuxing Chen
Cong-Zhao Zhou
Structure of a MacAB-like efflux pump from Streptococcus pneumoniae
description Bacterial ATP-binding cassette (ABC)-type efflux pumps are involved in the resistance of antibiotics and antimicrobial peptides. Here authors report the crystal structures and ATPase activity of the MacAB-like efflux pump from Streptococcus pneumonia and describe a putative substrate transport mechanism.
format article
author Hong-Bo Yang
Wen-Tao Hou
Meng-Ting Cheng
Yong-Liang Jiang
Yuxing Chen
Cong-Zhao Zhou
author_facet Hong-Bo Yang
Wen-Tao Hou
Meng-Ting Cheng
Yong-Liang Jiang
Yuxing Chen
Cong-Zhao Zhou
author_sort Hong-Bo Yang
title Structure of a MacAB-like efflux pump from Streptococcus pneumoniae
title_short Structure of a MacAB-like efflux pump from Streptococcus pneumoniae
title_full Structure of a MacAB-like efflux pump from Streptococcus pneumoniae
title_fullStr Structure of a MacAB-like efflux pump from Streptococcus pneumoniae
title_full_unstemmed Structure of a MacAB-like efflux pump from Streptococcus pneumoniae
title_sort structure of a macab-like efflux pump from streptococcus pneumoniae
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/771197c9eb5a453db314d079cce6a0ba
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