Structure of a MacAB-like efflux pump from Streptococcus pneumoniae
Bacterial ATP-binding cassette (ABC)-type efflux pumps are involved in the resistance of antibiotics and antimicrobial peptides. Here authors report the crystal structures and ATPase activity of the MacAB-like efflux pump from Streptococcus pneumonia and describe a putative substrate transport mecha...
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Nature Portfolio
2018
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oai:doaj.org-article:771197c9eb5a453db314d079cce6a0ba2021-12-02T15:33:37ZStructure of a MacAB-like efflux pump from Streptococcus pneumoniae10.1038/s41467-017-02741-42041-1723https://doaj.org/article/771197c9eb5a453db314d079cce6a0ba2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02741-4https://doaj.org/toc/2041-1723Bacterial ATP-binding cassette (ABC)-type efflux pumps are involved in the resistance of antibiotics and antimicrobial peptides. Here authors report the crystal structures and ATPase activity of the MacAB-like efflux pump from Streptococcus pneumonia and describe a putative substrate transport mechanism.Hong-Bo YangWen-Tao HouMeng-Ting ChengYong-Liang JiangYuxing ChenCong-Zhao ZhouNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Hong-Bo Yang Wen-Tao Hou Meng-Ting Cheng Yong-Liang Jiang Yuxing Chen Cong-Zhao Zhou Structure of a MacAB-like efflux pump from Streptococcus pneumoniae |
description |
Bacterial ATP-binding cassette (ABC)-type efflux pumps are involved in the resistance of antibiotics and antimicrobial peptides. Here authors report the crystal structures and ATPase activity of the MacAB-like efflux pump from Streptococcus pneumonia and describe a putative substrate transport mechanism. |
format |
article |
author |
Hong-Bo Yang Wen-Tao Hou Meng-Ting Cheng Yong-Liang Jiang Yuxing Chen Cong-Zhao Zhou |
author_facet |
Hong-Bo Yang Wen-Tao Hou Meng-Ting Cheng Yong-Liang Jiang Yuxing Chen Cong-Zhao Zhou |
author_sort |
Hong-Bo Yang |
title |
Structure of a MacAB-like efflux pump from Streptococcus pneumoniae |
title_short |
Structure of a MacAB-like efflux pump from Streptococcus pneumoniae |
title_full |
Structure of a MacAB-like efflux pump from Streptococcus pneumoniae |
title_fullStr |
Structure of a MacAB-like efflux pump from Streptococcus pneumoniae |
title_full_unstemmed |
Structure of a MacAB-like efflux pump from Streptococcus pneumoniae |
title_sort |
structure of a macab-like efflux pump from streptococcus pneumoniae |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/771197c9eb5a453db314d079cce6a0ba |
work_keys_str_mv |
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_version_ |
1718387088973365248 |