Structure of a MacAB-like efflux pump from Streptococcus pneumoniae

Bacterial ATP-binding cassette (ABC)-type efflux pumps are involved in the resistance of antibiotics and antimicrobial peptides. Here authors report the crystal structures and ATPase activity of the MacAB-like efflux pump from Streptococcus pneumonia and describe a putative substrate transport mecha...

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Bibliographic Details
Main Authors: Hong-Bo Yang, Wen-Tao Hou, Meng-Ting Cheng, Yong-Liang Jiang, Yuxing Chen, Cong-Zhao Zhou
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/771197c9eb5a453db314d079cce6a0ba
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