Mammographic texture features associated with contralateral breast cancer in the WECARE Study

Abstract To evaluate whether mammographic texture features were associated with second primary contralateral breast cancer (CBC) risk, we created a “texture risk score” using pre-treatment mammograms in a case–control study of 212 women with CBC and 223 controls with unilateral breast cancer. The te...

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Autores principales: Gordon P. Watt, Julia A. Knight, Christine Lin, Charles F. Lynch, Kathleen E. Malone, Esther M. John, Leslie Bernstein, Jennifer D. Brooks, Anne S. Reiner, Xiaolin Liang, Meghan Woods, Tuong L. Nguyen, John L. Hopper, Malcolm C. Pike, Jonine L. Bernstein
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Publicado: Nature Portfolio 2021
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spelling oai:doaj.org-article:77126e5aa8134831ad9757bfbf38d5682021-12-05T12:20:21ZMammographic texture features associated with contralateral breast cancer in the WECARE Study10.1038/s41523-021-00354-12374-4677https://doaj.org/article/77126e5aa8134831ad9757bfbf38d5682021-11-01T00:00:00Zhttps://doi.org/10.1038/s41523-021-00354-1https://doaj.org/toc/2374-4677Abstract To evaluate whether mammographic texture features were associated with second primary contralateral breast cancer (CBC) risk, we created a “texture risk score” using pre-treatment mammograms in a case–control study of 212 women with CBC and 223 controls with unilateral breast cancer. The texture risk score was associated with CBC (odds per adjusted standard deviation = 1.25, 95% CI 1.01–1.56) after adjustment for mammographic percent density and confounders. These results support the potential of texture features for CBC risk assessment of breast cancer survivors.Gordon P. WattJulia A. KnightChristine LinCharles F. LynchKathleen E. MaloneEsther M. JohnLeslie BernsteinJennifer D. BrooksAnne S. ReinerXiaolin LiangMeghan WoodsTuong L. NguyenJohn L. HopperMalcolm C. PikeJonine L. BernsteinNature PortfolioarticleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENnpj Breast Cancer, Vol 7, Iss 1, Pp 1-4 (2021)
institution DOAJ
collection DOAJ
language EN
topic Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Gordon P. Watt
Julia A. Knight
Christine Lin
Charles F. Lynch
Kathleen E. Malone
Esther M. John
Leslie Bernstein
Jennifer D. Brooks
Anne S. Reiner
Xiaolin Liang
Meghan Woods
Tuong L. Nguyen
John L. Hopper
Malcolm C. Pike
Jonine L. Bernstein
Mammographic texture features associated with contralateral breast cancer in the WECARE Study
description Abstract To evaluate whether mammographic texture features were associated with second primary contralateral breast cancer (CBC) risk, we created a “texture risk score” using pre-treatment mammograms in a case–control study of 212 women with CBC and 223 controls with unilateral breast cancer. The texture risk score was associated with CBC (odds per adjusted standard deviation = 1.25, 95% CI 1.01–1.56) after adjustment for mammographic percent density and confounders. These results support the potential of texture features for CBC risk assessment of breast cancer survivors.
format article
author Gordon P. Watt
Julia A. Knight
Christine Lin
Charles F. Lynch
Kathleen E. Malone
Esther M. John
Leslie Bernstein
Jennifer D. Brooks
Anne S. Reiner
Xiaolin Liang
Meghan Woods
Tuong L. Nguyen
John L. Hopper
Malcolm C. Pike
Jonine L. Bernstein
author_facet Gordon P. Watt
Julia A. Knight
Christine Lin
Charles F. Lynch
Kathleen E. Malone
Esther M. John
Leslie Bernstein
Jennifer D. Brooks
Anne S. Reiner
Xiaolin Liang
Meghan Woods
Tuong L. Nguyen
John L. Hopper
Malcolm C. Pike
Jonine L. Bernstein
author_sort Gordon P. Watt
title Mammographic texture features associated with contralateral breast cancer in the WECARE Study
title_short Mammographic texture features associated with contralateral breast cancer in the WECARE Study
title_full Mammographic texture features associated with contralateral breast cancer in the WECARE Study
title_fullStr Mammographic texture features associated with contralateral breast cancer in the WECARE Study
title_full_unstemmed Mammographic texture features associated with contralateral breast cancer in the WECARE Study
title_sort mammographic texture features associated with contralateral breast cancer in the wecare study
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/77126e5aa8134831ad9757bfbf38d568
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