RNAi screen in Drosophila cells reveals the involvement of the Tom complex in Chlamydia infection.

Chlamydia spp. are intracellular obligate bacterial pathogens that infect a wide range of host cells. Here, we show that C. caviae enters, replicates, and performs a complete developmental cycle in Drosophila SL2 cells. Using this model system, we have performed a genome-wide RNA interference screen...

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Bibliographic Details
Main Authors: Isabelle Derré, Marc Pypaert, Alice Dautry-Varsat, Hervé Agaisse
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2007
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Online Access:https://doaj.org/article/7717a8d745e948f4be845b5f2b79583b
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