Clinical Practice Guidelines on the Treatment of Patients with Cleft Lip, Alveolus, and Palate: An Executive Summary

Significant treatment variation exists in the Netherlands between teams treating patients with cleft lip, alveolus, and/or palate, resulting in a confusing and undesirable situation for patients, parents, and practitioners. Therefore, to optimize cleft care, clinical practice guidelines (CPGs) were...

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Autores principales:	Aebele B. Mink van der Molen, Johanna M. M. van Breugel, Nard G. Janssen, Ronald J. C. Admiraal, Leon N. A. van Adrichem, Frank Bierenbroodspot, Dirk Bittermann, Marie-José H. van den Boogaard, Pieter H. Broos, Janet J. M. Dijkstra-Putkamer, Martine C. M. van Gemert-Schriks, Andrea L. J. Kortlever, Chantal M. Mouës-Vink, Henriette F. N. Swanenburg de Veye, Nanouk van Tol-Verbeek, Christl Vermeij-Keers, Hester de Wilde, Anne Marie Kuijpers-Jagtman
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	cleft lip, alveolus and palate clinical practice guideline quality of health care recommendation clinical care treatment Medicine R
Acceso en línea:	https://doaj.org/article/771df64434cb48bbb9694c42cda4c4bf
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spelling	oai:doaj.org-article:771df64434cb48bbb9694c42cda4c4bf2021-11-11T17:29:18ZClinical Practice Guidelines on the Treatment of Patients with Cleft Lip, Alveolus, and Palate: An Executive Summary10.3390/jcm102148132077-0383https://doaj.org/article/771df64434cb48bbb9694c42cda4c4bf2021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/4813https://doaj.org/toc/2077-0383Significant treatment variation exists in the Netherlands between teams treating patients with cleft lip, alveolus, and/or palate, resulting in a confusing and undesirable situation for patients, parents, and practitioners. Therefore, to optimize cleft care, clinical practice guidelines (CPGs) were developed. The aim of this report is to describe CPG development, share the main recommendations, and indicate knowledge gaps regarding cleft care. Together with patients and parents, a multidisciplinary working group of representatives from all relevant disciplines assisted by two experienced epidemiologists identified the topics to be addressed in the CPGs. Searching the Medline, Embase, and Cochrane Library databases identified 5157 articles, 60 of which remained after applying inclusion and exclusion criteria. We rated the quality of the evidence from moderate to very low. The working group formulated 71 recommendations regarding genetic testing, feeding, lip and palate closure, hearing, hypernasality, bone grafting, orthodontics, psychosocial guidance, dentistry, osteotomy versus distraction, and rhinoplasty. The final CPGs were obtained after review by all stakeholders and allow cleft teams to base their treatment on current knowledge. With high-quality evidence lacking, the need for additional high-quality studies has become apparent.Aebele B. Mink van der MolenJohanna M. M. van BreugelNard G. JanssenRonald J. C. AdmiraalLeon N. A. van AdrichemFrank BierenbroodspotDirk BittermannMarie-José H. van den BoogaardPieter H. BroosJanet J. M. Dijkstra-PutkamerMartine C. M. van Gemert-SchriksAndrea L. J. KortleverChantal M. Mouës-VinkHenriette F. N. Swanenburg de VeyeNanouk van Tol-VerbeekChristl Vermeij-KeersHester de WildeAnne Marie Kuijpers-JagtmanMDPI AGarticlecleft lip, alveolus and palateclinical practice guidelinequality of health carerecommendation clinical caretreatmentMedicineRENJournal of Clinical Medicine, Vol 10, Iss 4813, p 4813 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cleft lip, alveolus and palate clinical practice guideline quality of health care recommendation clinical care treatment Medicine R
spellingShingle	cleft lip, alveolus and palate clinical practice guideline quality of health care recommendation clinical care treatment Medicine R Aebele B. Mink van der Molen Johanna M. M. van Breugel Nard G. Janssen Ronald J. C. Admiraal Leon N. A. van Adrichem Frank Bierenbroodspot Dirk Bittermann Marie-José H. van den Boogaard Pieter H. Broos Janet J. M. Dijkstra-Putkamer Martine C. M. van Gemert-Schriks Andrea L. J. Kortlever Chantal M. Mouës-Vink Henriette F. N. Swanenburg de Veye Nanouk van Tol-Verbeek Christl Vermeij-Keers Hester de Wilde Anne Marie Kuijpers-Jagtman Clinical Practice Guidelines on the Treatment of Patients with Cleft Lip, Alveolus, and Palate: An Executive Summary
description	Significant treatment variation exists in the Netherlands between teams treating patients with cleft lip, alveolus, and/or palate, resulting in a confusing and undesirable situation for patients, parents, and practitioners. Therefore, to optimize cleft care, clinical practice guidelines (CPGs) were developed. The aim of this report is to describe CPG development, share the main recommendations, and indicate knowledge gaps regarding cleft care. Together with patients and parents, a multidisciplinary working group of representatives from all relevant disciplines assisted by two experienced epidemiologists identified the topics to be addressed in the CPGs. Searching the Medline, Embase, and Cochrane Library databases identified 5157 articles, 60 of which remained after applying inclusion and exclusion criteria. We rated the quality of the evidence from moderate to very low. The working group formulated 71 recommendations regarding genetic testing, feeding, lip and palate closure, hearing, hypernasality, bone grafting, orthodontics, psychosocial guidance, dentistry, osteotomy versus distraction, and rhinoplasty. The final CPGs were obtained after review by all stakeholders and allow cleft teams to base their treatment on current knowledge. With high-quality evidence lacking, the need for additional high-quality studies has become apparent.
format	article
author	Aebele B. Mink van der Molen Johanna M. M. van Breugel Nard G. Janssen Ronald J. C. Admiraal Leon N. A. van Adrichem Frank Bierenbroodspot Dirk Bittermann Marie-José H. van den Boogaard Pieter H. Broos Janet J. M. Dijkstra-Putkamer Martine C. M. van Gemert-Schriks Andrea L. J. Kortlever Chantal M. Mouës-Vink Henriette F. N. Swanenburg de Veye Nanouk van Tol-Verbeek Christl Vermeij-Keers Hester de Wilde Anne Marie Kuijpers-Jagtman
author_facet	Aebele B. Mink van der Molen Johanna M. M. van Breugel Nard G. Janssen Ronald J. C. Admiraal Leon N. A. van Adrichem Frank Bierenbroodspot Dirk Bittermann Marie-José H. van den Boogaard Pieter H. Broos Janet J. M. Dijkstra-Putkamer Martine C. M. van Gemert-Schriks Andrea L. J. Kortlever Chantal M. Mouës-Vink Henriette F. N. Swanenburg de Veye Nanouk van Tol-Verbeek Christl Vermeij-Keers Hester de Wilde Anne Marie Kuijpers-Jagtman
author_sort	Aebele B. Mink van der Molen
title	Clinical Practice Guidelines on the Treatment of Patients with Cleft Lip, Alveolus, and Palate: An Executive Summary
title_short	Clinical Practice Guidelines on the Treatment of Patients with Cleft Lip, Alveolus, and Palate: An Executive Summary
title_full	Clinical Practice Guidelines on the Treatment of Patients with Cleft Lip, Alveolus, and Palate: An Executive Summary
title_fullStr	Clinical Practice Guidelines on the Treatment of Patients with Cleft Lip, Alveolus, and Palate: An Executive Summary
title_full_unstemmed	Clinical Practice Guidelines on the Treatment of Patients with Cleft Lip, Alveolus, and Palate: An Executive Summary
title_sort	clinical practice guidelines on the treatment of patients with cleft lip, alveolus, and palate: an executive summary
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/771df64434cb48bbb9694c42cda4c4bf
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Clinical Practice Guidelines on the Treatment of Patients with Cleft Lip, Alveolus, and Palate: An Executive Summary

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