Low-level Gestational Lead Exposure Alters Dendritic Spine Plasticity in the Hippocampus and Reduces Learning and Memory in Rats

Abstract Lead (Pb) is known to impair children’s cognitive function. It has been previously shown that developmental Pb exposure alters dendritic spine formation in hippocampal pyramidal neurons. However, the underlying mechanism has not yet been defined. In this study, a low-level gestational Pb ex...

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Autores principales: Zai-Hua Zhao, Gang Zheng, Tao Wang, Ke-jun Du, Xiao Han, Wen-Jing Luo, Xue-Feng Shen, Jing-Yuan Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/77203239fd184041ac68f8ae0b0aae3d
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