Low-level Gestational Lead Exposure Alters Dendritic Spine Plasticity in the Hippocampus and Reduces Learning and Memory in Rats
Abstract Lead (Pb) is known to impair children’s cognitive function. It has been previously shown that developmental Pb exposure alters dendritic spine formation in hippocampal pyramidal neurons. However, the underlying mechanism has not yet been defined. In this study, a low-level gestational Pb ex...
Guardado en:
Autores principales: | Zai-Hua Zhao, Gang Zheng, Tao Wang, Ke-jun Du, Xiao Han, Wen-Jing Luo, Xue-Feng Shen, Jing-Yuan Chen |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/77203239fd184041ac68f8ae0b0aae3d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
por: Adam C. Frank, et al.
Publicado: (2018) -
A spike-timing-dependent plasticity rule for dendritic spines
por: Sabrina Tazerart, et al.
Publicado: (2020) -
Location-dependent synaptic plasticity rules by dendritic spine cooperativity
por: Jens P. Weber, et al.
Publicado: (2016) -
High levels of 27-hydroxycholesterol results in synaptic plasticity alterations in the hippocampus
por: Raul Loera-Valencia, et al.
Publicado: (2021) -
Sex-specific features of spine densities in the hippocampus
por: Nicola Brandt, et al.
Publicado: (2020)