Donor Profile, Tissue Evaluation and Comparison of Voluntary and Motivated Corneal Donation in Nepal Eye Bank

Leena Bajracharya, 1 Sachit Kumar Bhandari, 2 Shankha Narayan Twyana 3 1Department of Cornea, Tilganga Institute of Ophthalmology, Kathmandu, Province No. 3, Nepal; 2Tilganga Institute of Ophthalmology, Kathmandu, Province No. 3, Nepal; 3Nepal Eye Bank, Tilganga Institute of Ophthalmology, Kathma...

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Autores principales:	Bajracharya L, Bhandari SK, Twyana SN
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	eye donation counsellor (edc) hospital corneal retrieval program (hcrp) tilganga institute of ophthalmology (tio) sightlife Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/7742003315c94110b3b833a85b017503
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spelling	oai:doaj.org-article:7742003315c94110b3b833a85b0175032021-12-02T04:37:48ZDonor Profile, Tissue Evaluation and Comparison of Voluntary and Motivated Corneal Donation in Nepal Eye Bank1177-5483https://doaj.org/article/7742003315c94110b3b833a85b0175032020-01-01T00:00:00Zhttps://www.dovepress.com/donor-profile-tissue-evaluation-and-comparison-of-voluntary-and-motiva-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Leena Bajracharya, 1 Sachit Kumar Bhandari, 2 Shankha Narayan Twyana 3 1Department of Cornea, Tilganga Institute of Ophthalmology, Kathmandu, Province No. 3, Nepal; 2Tilganga Institute of Ophthalmology, Kathmandu, Province No. 3, Nepal; 3Nepal Eye Bank, Tilganga Institute of Ophthalmology, Kathmandu, Province No. 3, NepalCorrespondence: Leena BajracharyaTilganga Institute of Ophthalmology, Gaushala, Bagmati Bridge, P. O. Box # 561, Kathmandu, Province No.3, NepalTel +977 1 4493775Fax +977- 1- 4474937Email lbajra@yahoo.comPurpose: Corneal problems is one of the major causes of blindness in developing countries like Nepal. This study intended to analyze donor and tissue profile of Nepal Eye Bank (NEB).Material and Methods: This was a cross-sectional descriptive type study. Data of corneal tissues collected by NEB from January 2015 to December 2016 were used in the study. Data collected were demographic profile, cause of death, type of corneal donation (whether voluntary or motivated), quality and utilization of tissues. A comparison was made between voluntary and motivated donors.Results: 1244 corneal tissues were retrieved from 639 donors. Mean age of donors was 49.4 years. 57.7% of the donors were male. There were almost equal number of donor deaths due to cardiovascular disease, 27.2%, and respiratory disease, 26.7%, followed by hanging, 17.8%. Majority of donors were motivated (n = 561, 87.7%). Mean death to preservation time was 5.79 hours (hrs). Of the harvested corneas, 1040 (83.6.%) were suitable for transplant with a mean endothelial cell count of 2850 ± 520 cells/mm 2; 16.4% were of poor tissue quality and 2.7% were seropositive. 76.2% of total tissues were of optical quality. Utilization rate of transplantable tissues was 97%. Tissues from motivated donors were significantly “younger” (p=0.0001), had better endothelial count (p=0.0001), and were of better quality (p=0.026) than those from voluntary donors.Conclusion: Motivated eye donation is a major and effective source of cornea collection in the eye bank under study with “younger” and better quality corneas compared to voluntary donors.Keywords: eye donation counselor, hospital corneal retrieval program, HCRP, Tilganga Institute of Ophthalmology, SightLifeBajracharya LBhandari SKTwyana SNDove Medical Pressarticleeye donation counsellor (edc)hospital corneal retrieval program (hcrp)tilganga institute of ophthalmology (tio)sightlifeOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 95-101 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	eye donation counsellor (edc) hospital corneal retrieval program (hcrp) tilganga institute of ophthalmology (tio) sightlife Ophthalmology RE1-994
spellingShingle	eye donation counsellor (edc) hospital corneal retrieval program (hcrp) tilganga institute of ophthalmology (tio) sightlife Ophthalmology RE1-994 Bajracharya L Bhandari SK Twyana SN Donor Profile, Tissue Evaluation and Comparison of Voluntary and Motivated Corneal Donation in Nepal Eye Bank
description	Leena Bajracharya, 1 Sachit Kumar Bhandari, 2 Shankha Narayan Twyana 3 1Department of Cornea, Tilganga Institute of Ophthalmology, Kathmandu, Province No. 3, Nepal; 2Tilganga Institute of Ophthalmology, Kathmandu, Province No. 3, Nepal; 3Nepal Eye Bank, Tilganga Institute of Ophthalmology, Kathmandu, Province No. 3, NepalCorrespondence: Leena BajracharyaTilganga Institute of Ophthalmology, Gaushala, Bagmati Bridge, P. O. Box # 561, Kathmandu, Province No.3, NepalTel +977 1 4493775Fax +977- 1- 4474937Email lbajra@yahoo.comPurpose: Corneal problems is one of the major causes of blindness in developing countries like Nepal. This study intended to analyze donor and tissue profile of Nepal Eye Bank (NEB).Material and Methods: This was a cross-sectional descriptive type study. Data of corneal tissues collected by NEB from January 2015 to December 2016 were used in the study. Data collected were demographic profile, cause of death, type of corneal donation (whether voluntary or motivated), quality and utilization of tissues. A comparison was made between voluntary and motivated donors.Results: 1244 corneal tissues were retrieved from 639 donors. Mean age of donors was 49.4 years. 57.7% of the donors were male. There were almost equal number of donor deaths due to cardiovascular disease, 27.2%, and respiratory disease, 26.7%, followed by hanging, 17.8%. Majority of donors were motivated (n = 561, 87.7%). Mean death to preservation time was 5.79 hours (hrs). Of the harvested corneas, 1040 (83.6.%) were suitable for transplant with a mean endothelial cell count of 2850 ± 520 cells/mm 2; 16.4% were of poor tissue quality and 2.7% were seropositive. 76.2% of total tissues were of optical quality. Utilization rate of transplantable tissues was 97%. Tissues from motivated donors were significantly “younger” (p=0.0001), had better endothelial count (p=0.0001), and were of better quality (p=0.026) than those from voluntary donors.Conclusion: Motivated eye donation is a major and effective source of cornea collection in the eye bank under study with “younger” and better quality corneas compared to voluntary donors.Keywords: eye donation counselor, hospital corneal retrieval program, HCRP, Tilganga Institute of Ophthalmology, SightLife
format	article
author	Bajracharya L Bhandari SK Twyana SN
author_facet	Bajracharya L Bhandari SK Twyana SN
author_sort	Bajracharya L
title	Donor Profile, Tissue Evaluation and Comparison of Voluntary and Motivated Corneal Donation in Nepal Eye Bank
title_short	Donor Profile, Tissue Evaluation and Comparison of Voluntary and Motivated Corneal Donation in Nepal Eye Bank
title_full	Donor Profile, Tissue Evaluation and Comparison of Voluntary and Motivated Corneal Donation in Nepal Eye Bank
title_fullStr	Donor Profile, Tissue Evaluation and Comparison of Voluntary and Motivated Corneal Donation in Nepal Eye Bank
title_full_unstemmed	Donor Profile, Tissue Evaluation and Comparison of Voluntary and Motivated Corneal Donation in Nepal Eye Bank
title_sort	donor profile, tissue evaluation and comparison of voluntary and motivated corneal donation in nepal eye bank
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/7742003315c94110b3b833a85b017503
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_version_	1718401128246280192

Donor Profile, Tissue Evaluation and Comparison of Voluntary and Motivated Corneal Donation in Nepal Eye Bank

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