Antimicrobial Effect of Calcium Hydroxide Combined with Electrolyzed Superoxidized Solution at Neutral pH on Enterococcus faecalis Growth

Objective. To evaluate the effect of the combination of calcium hydroxide (Ca(OH)2) and a novel electrolyzed superoxidized solution at neutral pH, known as OxOral® on Enterococcus faecalis growth in root canals. Methods. Sixty human teeth were used, from which root canals were infected and randomly...

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Autores principales:	Héctor Armando Jimenez-Gonzalez, María Argelia Akemi Nakagoshi-Cepeda, Sergio Eduardo Nakagoshi-Cepeda, Víctor Hugo Urrutia-Baca, Myriam Angélica De La Garza-Ramos, Juan Manuel Solis-Soto, Ricardo Gomez-Flores, Patricia Tamez-Guerra
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/77487e14b8534b709a08fa9a1e6bc72e
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spelling	oai:doaj.org-article:77487e14b8534b709a08fa9a1e6bc72e2021-11-22T01:11:09ZAntimicrobial Effect of Calcium Hydroxide Combined with Electrolyzed Superoxidized Solution at Neutral pH on Enterococcus faecalis Growth2314-614110.1155/2021/6960143https://doaj.org/article/77487e14b8534b709a08fa9a1e6bc72e2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/6960143https://doaj.org/toc/2314-6141Objective. To evaluate the effect of the combination of calcium hydroxide (Ca(OH)2) and a novel electrolyzed superoxidized solution at neutral pH, known as OxOral® on Enterococcus faecalis growth in root canals. Methods. Sixty human teeth were used, from which root canals were infected and randomly divided into the following treatment groups: saline solution, saline solution plus Ca(OH)2, OxOral®, and OxOral® plus Ca(OH)2. Results. A permanent reduction in bacterial growth was observed at days 1, 6, 12, and 18 after OxOral® plus Ca(OH)2 treatment from 4.4±0.074 log10 CFU/mL to 0.0±0.001 log10 CFU/mL. In addition, alkaline conditions maintenance was observed from application time (pH=12.2±0.033) to 18 d posttreatment (pH=12.6±0.083). Conclusion. The combination of OxOral® and Ca(OH)2 provides an alkaline pH and inhibits E. faecalis growth into the root canals. Our study opens the possibility for further research on the use of OxOral® in endodontic therapy.Héctor Armando Jimenez-GonzalezMaría Argelia Akemi Nakagoshi-CepedaSergio Eduardo Nakagoshi-CepedaVíctor Hugo Urrutia-BacaMyriam Angélica De La Garza-RamosJuan Manuel Solis-SotoRicardo Gomez-FloresPatricia Tamez-GuerraHindawi LimitedarticleMedicineRENBioMed Research International, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R Héctor Armando Jimenez-Gonzalez María Argelia Akemi Nakagoshi-Cepeda Sergio Eduardo Nakagoshi-Cepeda Víctor Hugo Urrutia-Baca Myriam Angélica De La Garza-Ramos Juan Manuel Solis-Soto Ricardo Gomez-Flores Patricia Tamez-Guerra Antimicrobial Effect of Calcium Hydroxide Combined with Electrolyzed Superoxidized Solution at Neutral pH on Enterococcus faecalis Growth
description	Objective. To evaluate the effect of the combination of calcium hydroxide (Ca(OH)2) and a novel electrolyzed superoxidized solution at neutral pH, known as OxOral® on Enterococcus faecalis growth in root canals. Methods. Sixty human teeth were used, from which root canals were infected and randomly divided into the following treatment groups: saline solution, saline solution plus Ca(OH)2, OxOral®, and OxOral® plus Ca(OH)2. Results. A permanent reduction in bacterial growth was observed at days 1, 6, 12, and 18 after OxOral® plus Ca(OH)2 treatment from 4.4±0.074 log10 CFU/mL to 0.0±0.001 log10 CFU/mL. In addition, alkaline conditions maintenance was observed from application time (pH=12.2±0.033) to 18 d posttreatment (pH=12.6±0.083). Conclusion. The combination of OxOral® and Ca(OH)2 provides an alkaline pH and inhibits E. faecalis growth into the root canals. Our study opens the possibility for further research on the use of OxOral® in endodontic therapy.
format	article
author	Héctor Armando Jimenez-Gonzalez María Argelia Akemi Nakagoshi-Cepeda Sergio Eduardo Nakagoshi-Cepeda Víctor Hugo Urrutia-Baca Myriam Angélica De La Garza-Ramos Juan Manuel Solis-Soto Ricardo Gomez-Flores Patricia Tamez-Guerra
author_facet	Héctor Armando Jimenez-Gonzalez María Argelia Akemi Nakagoshi-Cepeda Sergio Eduardo Nakagoshi-Cepeda Víctor Hugo Urrutia-Baca Myriam Angélica De La Garza-Ramos Juan Manuel Solis-Soto Ricardo Gomez-Flores Patricia Tamez-Guerra
author_sort	Héctor Armando Jimenez-Gonzalez
title	Antimicrobial Effect of Calcium Hydroxide Combined with Electrolyzed Superoxidized Solution at Neutral pH on Enterococcus faecalis Growth
title_short	Antimicrobial Effect of Calcium Hydroxide Combined with Electrolyzed Superoxidized Solution at Neutral pH on Enterococcus faecalis Growth
title_full	Antimicrobial Effect of Calcium Hydroxide Combined with Electrolyzed Superoxidized Solution at Neutral pH on Enterococcus faecalis Growth
title_fullStr	Antimicrobial Effect of Calcium Hydroxide Combined with Electrolyzed Superoxidized Solution at Neutral pH on Enterococcus faecalis Growth
title_full_unstemmed	Antimicrobial Effect of Calcium Hydroxide Combined with Electrolyzed Superoxidized Solution at Neutral pH on Enterococcus faecalis Growth
title_sort	antimicrobial effect of calcium hydroxide combined with electrolyzed superoxidized solution at neutral ph on enterococcus faecalis growth
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/77487e14b8534b709a08fa9a1e6bc72e
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Antimicrobial Effect of Calcium Hydroxide Combined with Electrolyzed Superoxidized Solution at Neutral pH on Enterococcus faecalis Growth

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