Discovery of <italic toggle="yes">mcr-1</italic>-Mediated Colistin Resistance in a Highly Virulent <named-content content-type="genus-species">Escherichia coli</named-content> Lineage

Discovery of <italic toggle="yes">mcr-1</italic>-Mediated Colistin Resistance in a Highly Virulent <named-content content-type="genus-species">Escherichia coli</named-content> Lineage

ABSTRACT Resistance to last-line polymyxins mediated by the plasmid-borne mobile colistin resistance gene (mcr-1) represents a new threat to global human health. Here we present the complete genome sequence of an mcr-1-positive multidrug-resistant Escherichia coli strain (MS8345). We show that MS834...

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Bibliographic Details
Main Authors: Brian M. Forde, Hosam M. Zowawi, Patrick N. A. Harris, Leah Roberts, Emad Ibrahim, Nissar Shaikh, Anand Deshmukh, Mazen A. Sid Ahmed, Muna Al Maslamani, Kyra Cottrell, Ella Trembizki, Lana Sundac, Heidi H. Yu, Jian Li, Mark A. Schembri, David M. Whiley, David L. Paterson, Scott A. Beatson
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
Escherichia coli
antibiotic resistance
genome analysis
Microbiology
QR1-502
Online Access:https://doaj.org/article/774be1daa8cb4e5d8b8f79dd7eb81405
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