Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy

BACKGROUND: Gallstone disease is one of the commonest surgical ailments encountered in our setup. Its prevalence in India varies from 2% to 29%. Although cholelithiasis accounts for more than 95% of gall bladder related disease, routine histopathological examination (HPE) is vital. It reveals a myri...

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Autores principales:	Ashesh Kumar Jha, Ashraf Ali, Manoj Kumar, Punam Prasad Badhani, Niroop B S. Murthy, Kumar Chandrakant
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	cholecystectomy chronic cholecystitis gallbladder gallbladder carcinoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/774d2880edd049ed8c4c9015c2082246
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spelling	oai:doaj.org-article:774d2880edd049ed8c4c9015c20822462021-11-12T10:17:19ZOutcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy1477-316310.4103/jcar.jcar_19_21https://doaj.org/article/774d2880edd049ed8c4c9015c20822462021-01-01T00:00:00Zhttp://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2021;volume=20;issue=1;spage=19;epage=19;aulast=Jhahttps://doaj.org/toc/1477-3163BACKGROUND: Gallstone disease is one of the commonest surgical ailments encountered in our setup. Its prevalence in India varies from 2% to 29%. Although cholelithiasis accounts for more than 95% of gall bladder related disease, routine histopathological examination (HPE) is vital. It reveals a myriad of benign as well as the malignant surgical pathology of the gallbladder (GB). This part of the world is considered as an endemic region for GB carcinoma as well as gallstone disease. This study intends to evaluate the outcome of the routine HPE of laparoscopic cholecystectomy specimens.METHODS: This retrospective observational study evaluated the results of the routine HPE of elective laparoscopic cholecystectomy specimens of single tertiary care center. Patients suspected or diagnosed with carcinoma gall bladder were excluded. Demographic data such as age, sex, and pathology results were recorded.RESULTS: From January 2017 to December 2019, HPEs of 921 patients who had undergone laparoscopic cholecystectomy specimens were analyzed. 97.6% specimens had benign lesion of which chronic calculus cholecystitis was predominantly high (95.01%) followed by cholesterosis (9.9%) and xanthogranulomatous cholecystitis (6.51%). Incidental carcinoma gall bladder was observed in 17 specimens accounting for 1.85%. Mean age of patients who underwent cholecystectomy was 43.10 ± 13.90 with female to male ratio of 3.23:1.CONCLUSION: Chronic calculus cholecystitis was the most common gall bladder disease with high female preponderance to all GB pathologies. This study affirms the importance of routine HPE after cholecystectomy as early incidental detection of carcinoma gall bladder alters the postoperative management approach and patients are expected to have a better outcome with it.Ashesh Kumar JhaAshraf AliManoj KumarManoj KumarPunam Prasad BadhaniNiroop B S. MurthyKumar ChandrakantWolters Kluwer Medknow Publicationsarticlecholecystectomychronic cholecystitisgallbladdergallbladder carcinomaNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENJournal of Carcinogenesis, Vol 20, Iss 1, Pp 19-19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cholecystectomy chronic cholecystitis gallbladder gallbladder carcinoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	cholecystectomy chronic cholecystitis gallbladder gallbladder carcinoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Ashesh Kumar Jha Ashraf Ali Manoj Kumar Manoj Kumar Punam Prasad Badhani Niroop B S. Murthy Kumar Chandrakant Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
description	BACKGROUND: Gallstone disease is one of the commonest surgical ailments encountered in our setup. Its prevalence in India varies from 2% to 29%. Although cholelithiasis accounts for more than 95% of gall bladder related disease, routine histopathological examination (HPE) is vital. It reveals a myriad of benign as well as the malignant surgical pathology of the gallbladder (GB). This part of the world is considered as an endemic region for GB carcinoma as well as gallstone disease. This study intends to evaluate the outcome of the routine HPE of laparoscopic cholecystectomy specimens.METHODS: This retrospective observational study evaluated the results of the routine HPE of elective laparoscopic cholecystectomy specimens of single tertiary care center. Patients suspected or diagnosed with carcinoma gall bladder were excluded. Demographic data such as age, sex, and pathology results were recorded.RESULTS: From January 2017 to December 2019, HPEs of 921 patients who had undergone laparoscopic cholecystectomy specimens were analyzed. 97.6% specimens had benign lesion of which chronic calculus cholecystitis was predominantly high (95.01%) followed by cholesterosis (9.9%) and xanthogranulomatous cholecystitis (6.51%). Incidental carcinoma gall bladder was observed in 17 specimens accounting for 1.85%. Mean age of patients who underwent cholecystectomy was 43.10 ± 13.90 with female to male ratio of 3.23:1.CONCLUSION: Chronic calculus cholecystitis was the most common gall bladder disease with high female preponderance to all GB pathologies. This study affirms the importance of routine HPE after cholecystectomy as early incidental detection of carcinoma gall bladder alters the postoperative management approach and patients are expected to have a better outcome with it.
format	article
author	Ashesh Kumar Jha Ashraf Ali Manoj Kumar Manoj Kumar Punam Prasad Badhani Niroop B S. Murthy Kumar Chandrakant
author_facet	Ashesh Kumar Jha Ashraf Ali Manoj Kumar Manoj Kumar Punam Prasad Badhani Niroop B S. Murthy Kumar Chandrakant
author_sort	Ashesh Kumar Jha
title	Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
title_short	Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
title_full	Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
title_fullStr	Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
title_full_unstemmed	Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
title_sort	outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/774d2880edd049ed8c4c9015c2082246
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Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy

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