A review on current nanomaterials and their drug conjugate for targeted breast cancer treatment

Joanna Jinling Lee,1 Latifah Saiful Yazan,2 Che Azurahanim Che Abdullah3 1Laboratory of Molecular Biomedicine, Institute of Bioscience, 2Department of Biomedical Science, Faculty of Medicine and Health Sciences, 3Department of Physics, Faculty of Science, Universiti Putra Malaysia, Selangor, Malays...

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Autores principales:	Lee JJ, Saiful Yazan L, Che Abdullah CA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Breast cancer therapeutic strategies nanomedicine advantages disadvantages Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/7759961dcaf24cafa0df1cdf94647967
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spelling	oai:doaj.org-article:7759961dcaf24cafa0df1cdf946479672021-12-02T02:45:54ZA review on current nanomaterials and their drug conjugate for targeted breast cancer treatment1178-2013https://doaj.org/article/7759961dcaf24cafa0df1cdf946479672017-03-01T00:00:00Zhttps://www.dovepress.com/a-review-on-current-nanomaterials-and-their-drug-conjugate-for-targete-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Joanna Jinling Lee,1 Latifah Saiful Yazan,2 Che Azurahanim Che Abdullah3 1Laboratory of Molecular Biomedicine, Institute of Bioscience, 2Department of Biomedical Science, Faculty of Medicine and Health Sciences, 3Department of Physics, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia Abstract: Breast cancer is the most common malignancy worldwide, especially among women, with substantial after-treatment effects. The survival rates of breast cancer have decreased over the years even with the existence of various therapeutic strategies, specifically, chemotherapy. Clinical drugs administered for breast cancer appear to be non-targeting to specific cancer sites leading to severe side effects and potentially harming healthy cells instead of just killing cancer cells. This leads to the need for designing a targeted drug delivery system. Nanomaterials, both organic and inorganic, are potential drug nanocarriers with the ability of targeting, imaging and tracking. Various types of nanomaterials have been actively researched together with their drug conjugate. In this review, we focus on selected nanomaterials, namely solid-lipid, liposomal, polymeric, magnetic nanoparticles, quantum dots, and carbon nanotubes and their drug conjugates, for breast cancer studies. Their advantages, disadvantages and previously conducted studies were highlighted. Keywords: breast cancer, therapeutic strategies, nanomedicine, advantages, disadvantagesLee JJSaiful Yazan LChe Abdullah CADove Medical PressarticleBreast cancertherapeutic strategiesnanomedicineadvantagesdisadvantagesMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 12, Pp 2373-2384 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Breast cancer therapeutic strategies nanomedicine advantages disadvantages Medicine (General) R5-920
spellingShingle	Breast cancer therapeutic strategies nanomedicine advantages disadvantages Medicine (General) R5-920 Lee JJ Saiful Yazan L Che Abdullah CA A review on current nanomaterials and their drug conjugate for targeted breast cancer treatment
description	Joanna Jinling Lee,1 Latifah Saiful Yazan,2 Che Azurahanim Che Abdullah3 1Laboratory of Molecular Biomedicine, Institute of Bioscience, 2Department of Biomedical Science, Faculty of Medicine and Health Sciences, 3Department of Physics, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia Abstract: Breast cancer is the most common malignancy worldwide, especially among women, with substantial after-treatment effects. The survival rates of breast cancer have decreased over the years even with the existence of various therapeutic strategies, specifically, chemotherapy. Clinical drugs administered for breast cancer appear to be non-targeting to specific cancer sites leading to severe side effects and potentially harming healthy cells instead of just killing cancer cells. This leads to the need for designing a targeted drug delivery system. Nanomaterials, both organic and inorganic, are potential drug nanocarriers with the ability of targeting, imaging and tracking. Various types of nanomaterials have been actively researched together with their drug conjugate. In this review, we focus on selected nanomaterials, namely solid-lipid, liposomal, polymeric, magnetic nanoparticles, quantum dots, and carbon nanotubes and their drug conjugates, for breast cancer studies. Their advantages, disadvantages and previously conducted studies were highlighted. Keywords: breast cancer, therapeutic strategies, nanomedicine, advantages, disadvantages
format	article
author	Lee JJ Saiful Yazan L Che Abdullah CA
author_facet	Lee JJ Saiful Yazan L Che Abdullah CA
author_sort	Lee JJ
title	A review on current nanomaterials and their drug conjugate for targeted breast cancer treatment
title_short	A review on current nanomaterials and their drug conjugate for targeted breast cancer treatment
title_full	A review on current nanomaterials and their drug conjugate for targeted breast cancer treatment
title_fullStr	A review on current nanomaterials and their drug conjugate for targeted breast cancer treatment
title_full_unstemmed	A review on current nanomaterials and their drug conjugate for targeted breast cancer treatment
title_sort	review on current nanomaterials and their drug conjugate for targeted breast cancer treatment
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/7759961dcaf24cafa0df1cdf94647967
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A review on current nanomaterials and their drug conjugate for targeted breast cancer treatment

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