Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

High levels of Fusobacterium nucleatum have been associated with poor overall survival in patients with colorectal and esophageal cancer. Here, the authors show that F. nucleatum is abundant in breast cancer samples and that the colonization by F. nucleatum accelerates tumor growth and metastasis in...

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Autores principales:	Lishay Parhi, Tamar Alon-Maimon, Asaf Sol, Deborah Nejman, Amjad Shhadeh, Tanya Fainsod-Levi, Olga Yajuk, Batya Isaacson, Jawad Abed, Naseem Maalouf, Aviram Nissan, Judith Sandbank, Einav Yehuda-Shnaidman, Falk Ponath, Jörg Vogel, Ofer Mandelboim, Zvi Granot, Ravid Straussman, Gilad Bachrach
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/776f0ce45a884e0eb485ae59e2c301df
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spelling	oai:doaj.org-article:776f0ce45a884e0eb485ae59e2c301df2021-12-02T18:02:47ZBreast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression10.1038/s41467-020-16967-22041-1723https://doaj.org/article/776f0ce45a884e0eb485ae59e2c301df2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16967-2https://doaj.org/toc/2041-1723High levels of Fusobacterium nucleatum have been associated with poor overall survival in patients with colorectal and esophageal cancer. Here, the authors show that F. nucleatum is abundant in breast cancer samples and that the colonization by F. nucleatum accelerates tumor growth and metastasis in preclinical breast cancer models.Lishay ParhiTamar Alon-MaimonAsaf SolDeborah NejmanAmjad ShhadehTanya Fainsod-LeviOlga YajukBatya IsaacsonJawad AbedNaseem MaaloufAviram NissanJudith SandbankEinav Yehuda-ShnaidmanFalk PonathJörg VogelOfer MandelboimZvi GranotRavid StraussmanGilad BachrachNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lishay Parhi Tamar Alon-Maimon Asaf Sol Deborah Nejman Amjad Shhadeh Tanya Fainsod-Levi Olga Yajuk Batya Isaacson Jawad Abed Naseem Maalouf Aviram Nissan Judith Sandbank Einav Yehuda-Shnaidman Falk Ponath Jörg Vogel Ofer Mandelboim Zvi Granot Ravid Straussman Gilad Bachrach Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression
description	High levels of Fusobacterium nucleatum have been associated with poor overall survival in patients with colorectal and esophageal cancer. Here, the authors show that F. nucleatum is abundant in breast cancer samples and that the colonization by F. nucleatum accelerates tumor growth and metastasis in preclinical breast cancer models.
format	article
author	Lishay Parhi Tamar Alon-Maimon Asaf Sol Deborah Nejman Amjad Shhadeh Tanya Fainsod-Levi Olga Yajuk Batya Isaacson Jawad Abed Naseem Maalouf Aviram Nissan Judith Sandbank Einav Yehuda-Shnaidman Falk Ponath Jörg Vogel Ofer Mandelboim Zvi Granot Ravid Straussman Gilad Bachrach
author_facet	Lishay Parhi Tamar Alon-Maimon Asaf Sol Deborah Nejman Amjad Shhadeh Tanya Fainsod-Levi Olga Yajuk Batya Isaacson Jawad Abed Naseem Maalouf Aviram Nissan Judith Sandbank Einav Yehuda-Shnaidman Falk Ponath Jörg Vogel Ofer Mandelboim Zvi Granot Ravid Straussman Gilad Bachrach
author_sort	Lishay Parhi
title	Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression
title_short	Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression
title_full	Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression
title_fullStr	Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression
title_full_unstemmed	Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression
title_sort	breast cancer colonization by fusobacterium nucleatum accelerates tumor growth and metastatic progression
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/776f0ce45a884e0eb485ae59e2c301df
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Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

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