Genomic Uniqueness of Local Sheep Breeds From Morocco

Sheep farming is a major source of meat in Morocco and plays a key role in the country’s agriculture. This study aims at characterizing the whole-genome diversity and demographic history of the main Moroccan sheep breeds, as well as to identify selection signatures within and between breeds. Whole g...

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Autores principales:	Abdessamad Ouhrouch, Simon Boitard, Frédéric Boyer, Bertrand Servin, Anne Da Silva, François Pompanon, Abdelmajid Haddioui, Badr Benjelloun
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	sheep whole genome sequences local breeds demography selection signatures Genetics QH426-470
Acceso en línea:	https://doaj.org/article/777bd040924b4101bda99b1fd07f2179
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spelling	oai:doaj.org-article:777bd040924b4101bda99b1fd07f21792021-12-02T11:27:52ZGenomic Uniqueness of Local Sheep Breeds From Morocco1664-802110.3389/fgene.2021.723599https://doaj.org/article/777bd040924b4101bda99b1fd07f21792021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fgene.2021.723599/fullhttps://doaj.org/toc/1664-8021Sheep farming is a major source of meat in Morocco and plays a key role in the country’s agriculture. This study aims at characterizing the whole-genome diversity and demographic history of the main Moroccan sheep breeds, as well as to identify selection signatures within and between breeds. Whole genome data from 87 individuals representing the five predominant local breeds were used to estimate their level of neutral genetic diversity and to infer the variation of their effective population size over time. In addition, we used two methods to detect selection signatures: either for detecting selective sweeps within each breed separately or by detecting differentially selected regions by contrasting different breeds. We identified hundreds of genomic regions putatively under selection, which related to several biological terms involved in local adaptation or the expression of zootechnical performances such as Growth, UV protection, Cell maturation or Feeding behavior. The results of this study revealed selection signatures in genes that have an important role in traits of interest and increased our understanding of how genetic diversity is distributed in these local breeds. Thus, Moroccan local sheep breeds exhibit both a high genetic diversity and a large set of adaptive variations, and therefore, represent a valuable genetic resource for the conservation of sheep in the context of climate change.Abdessamad OuhrouchAbdessamad OuhrouchSimon BoitardFrédéric BoyerBertrand ServinAnne Da SilvaFrançois PompanonAbdelmajid HaddiouiBadr BenjellounFrontiers Media S.A.articlesheepwhole genome sequenceslocal breedsdemographyselection signaturesGeneticsQH426-470ENFrontiers in Genetics, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	sheep whole genome sequences local breeds demography selection signatures Genetics QH426-470
spellingShingle	sheep whole genome sequences local breeds demography selection signatures Genetics QH426-470 Abdessamad Ouhrouch Abdessamad Ouhrouch Simon Boitard Frédéric Boyer Bertrand Servin Anne Da Silva François Pompanon Abdelmajid Haddioui Badr Benjelloun Genomic Uniqueness of Local Sheep Breeds From Morocco
description	Sheep farming is a major source of meat in Morocco and plays a key role in the country’s agriculture. This study aims at characterizing the whole-genome diversity and demographic history of the main Moroccan sheep breeds, as well as to identify selection signatures within and between breeds. Whole genome data from 87 individuals representing the five predominant local breeds were used to estimate their level of neutral genetic diversity and to infer the variation of their effective population size over time. In addition, we used two methods to detect selection signatures: either for detecting selective sweeps within each breed separately or by detecting differentially selected regions by contrasting different breeds. We identified hundreds of genomic regions putatively under selection, which related to several biological terms involved in local adaptation or the expression of zootechnical performances such as Growth, UV protection, Cell maturation or Feeding behavior. The results of this study revealed selection signatures in genes that have an important role in traits of interest and increased our understanding of how genetic diversity is distributed in these local breeds. Thus, Moroccan local sheep breeds exhibit both a high genetic diversity and a large set of adaptive variations, and therefore, represent a valuable genetic resource for the conservation of sheep in the context of climate change.
format	article
author	Abdessamad Ouhrouch Abdessamad Ouhrouch Simon Boitard Frédéric Boyer Bertrand Servin Anne Da Silva François Pompanon Abdelmajid Haddioui Badr Benjelloun
author_facet	Abdessamad Ouhrouch Abdessamad Ouhrouch Simon Boitard Frédéric Boyer Bertrand Servin Anne Da Silva François Pompanon Abdelmajid Haddioui Badr Benjelloun
author_sort	Abdessamad Ouhrouch
title	Genomic Uniqueness of Local Sheep Breeds From Morocco
title_short	Genomic Uniqueness of Local Sheep Breeds From Morocco
title_full	Genomic Uniqueness of Local Sheep Breeds From Morocco
title_fullStr	Genomic Uniqueness of Local Sheep Breeds From Morocco
title_full_unstemmed	Genomic Uniqueness of Local Sheep Breeds From Morocco
title_sort	genomic uniqueness of local sheep breeds from morocco
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/777bd040924b4101bda99b1fd07f2179
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Genomic Uniqueness of Local Sheep Breeds From Morocco

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