Chest Radiographs and CT Findings during Healthcare Workers’ Tuberculosis Screening Using Interferon- Gamma Release Assay: Retrospective Observational Study

Purpose To investigate the incidence of tuberculosis (TB) in healthcare workers (HCWs) with positive interferon-gamma release assay (IGRA) results based on chest X-ray (CXR) and CT findings and determine the role of imaging in the diagnosis of TB. Materials and Methods Among 1976 hospital personn...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ye Ra Choi, Jung-Kyu Lee, Eun Young Heo, Deog Kyeom Kim, Kwang Nam Jin
Formato:	article
Lenguaje:	EN KO
Publicado:	The Korean Society of Radiology 2021
Materias:	thorax x-rays tomography x ray computed tuberculosis interferon gamma release tests Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/777e1f8c902e43549f6217d775d731cc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:777e1f8c902e43549f6217d775d731cc
record_format	dspace
spelling	oai:doaj.org-article:777e1f8c902e43549f6217d775d731cc2021-11-29T11:08:31ZChest Radiographs and CT Findings during Healthcare Workers’ Tuberculosis Screening Using Interferon- Gamma Release Assay: Retrospective Observational Study2288-2928https://doaj.org/article/777e1f8c902e43549f6217d775d731cc2021-11-01T00:00:00Zhttps://doi.org/10.3348/jksr.2020.0160https://doaj.org/toc/2288-2928Purpose To investigate the incidence of tuberculosis (TB) in healthcare workers (HCWs) with positive interferon-gamma release assay (IGRA) results based on chest X-ray (CXR) and CT findings and determine the role of imaging in the diagnosis of TB. Materials and Methods Among 1976 hospital personnel screened for TB using IGRA, IGRApositive subjects were retrospectively investigated. Clustered nodular and/or linear streaky opacities in the upper lung zone were considered positive on CXR. The CT findings were classified as active, indeterminate, inactive, or normal. The active or indeterminate class was considered CT-positive. Results IGRA was positive in 255 subjects (12.9%). CXR and CT were performed in 249 (99.2%) and 113 subjects (45.0%), respectively. CXR- and CT-positive findings were found in 7 of 249 (2.8%) and 9 of 113 (8.0%) patients, respectively. Among the nine CT-positive subjects, active and indeterminate TB findings were found in 6 (5.3%) and 3 (2.7%) patients, respectively. Microbiological tests, including acid-fast bacilli staining, culture, and polymerase chain action for TB, were negative in all nine CT-positive subjects. Empirical anti-TB medications were administered to 9 CT-positive subjects, and 3 of these nine subjects were CXR-negative for pulmonary TB. Conclusion CT helped diagnose asymptomatic TB in IGRA-positive HCWs. Ye Ra ChoiJung-Kyu LeeEun Young HeoDeog Kyeom KimKwang Nam JinThe Korean Society of Radiologyarticlethoraxx-raystomographyx ray computedtuberculosisinterferon gamma release testsMedical physics. Medical radiology. Nuclear medicineR895-920ENKO대한영상의학회지, Vol 82, Iss 6, Pp 1524-1533 (2021)
institution	DOAJ
collection	DOAJ
language	EN KO
topic	thorax x-rays tomography x ray computed tuberculosis interferon gamma release tests Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	thorax x-rays tomography x ray computed tuberculosis interferon gamma release tests Medical physics. Medical radiology. Nuclear medicine R895-920 Ye Ra Choi Jung-Kyu Lee Eun Young Heo Deog Kyeom Kim Kwang Nam Jin Chest Radiographs and CT Findings during Healthcare Workers’ Tuberculosis Screening Using Interferon- Gamma Release Assay: Retrospective Observational Study
description	Purpose To investigate the incidence of tuberculosis (TB) in healthcare workers (HCWs) with positive interferon-gamma release assay (IGRA) results based on chest X-ray (CXR) and CT findings and determine the role of imaging in the diagnosis of TB. Materials and Methods Among 1976 hospital personnel screened for TB using IGRA, IGRApositive subjects were retrospectively investigated. Clustered nodular and/or linear streaky opacities in the upper lung zone were considered positive on CXR. The CT findings were classified as active, indeterminate, inactive, or normal. The active or indeterminate class was considered CT-positive. Results IGRA was positive in 255 subjects (12.9%). CXR and CT were performed in 249 (99.2%) and 113 subjects (45.0%), respectively. CXR- and CT-positive findings were found in 7 of 249 (2.8%) and 9 of 113 (8.0%) patients, respectively. Among the nine CT-positive subjects, active and indeterminate TB findings were found in 6 (5.3%) and 3 (2.7%) patients, respectively. Microbiological tests, including acid-fast bacilli staining, culture, and polymerase chain action for TB, were negative in all nine CT-positive subjects. Empirical anti-TB medications were administered to 9 CT-positive subjects, and 3 of these nine subjects were CXR-negative for pulmonary TB. Conclusion CT helped diagnose asymptomatic TB in IGRA-positive HCWs.
format	article
author	Ye Ra Choi Jung-Kyu Lee Eun Young Heo Deog Kyeom Kim Kwang Nam Jin
author_facet	Ye Ra Choi Jung-Kyu Lee Eun Young Heo Deog Kyeom Kim Kwang Nam Jin
author_sort	Ye Ra Choi
title	Chest Radiographs and CT Findings during Healthcare Workers’ Tuberculosis Screening Using Interferon- Gamma Release Assay: Retrospective Observational Study
title_short	Chest Radiographs and CT Findings during Healthcare Workers’ Tuberculosis Screening Using Interferon- Gamma Release Assay: Retrospective Observational Study
title_full	Chest Radiographs and CT Findings during Healthcare Workers’ Tuberculosis Screening Using Interferon- Gamma Release Assay: Retrospective Observational Study
title_fullStr	Chest Radiographs and CT Findings during Healthcare Workers’ Tuberculosis Screening Using Interferon- Gamma Release Assay: Retrospective Observational Study
title_full_unstemmed	Chest Radiographs and CT Findings during Healthcare Workers’ Tuberculosis Screening Using Interferon- Gamma Release Assay: Retrospective Observational Study
title_sort	chest radiographs and ct findings during healthcare workers’ tuberculosis screening using interferon- gamma release assay: retrospective observational study
publisher	The Korean Society of Radiology
publishDate	2021
url	https://doaj.org/article/777e1f8c902e43549f6217d775d731cc
work_keys_str_mv	AT yerachoi chestradiographsandctfindingsduringhealthcareworkerstuberculosisscreeningusinginterferongammareleaseassayretrospectiveobservationalstudy AT jungkyulee chestradiographsandctfindingsduringhealthcareworkerstuberculosisscreeningusinginterferongammareleaseassayretrospectiveobservationalstudy AT eunyoungheo chestradiographsandctfindingsduringhealthcareworkerstuberculosisscreeningusinginterferongammareleaseassayretrospectiveobservationalstudy AT deogkyeomkim chestradiographsandctfindingsduringhealthcareworkerstuberculosisscreeningusinginterferongammareleaseassayretrospectiveobservationalstudy AT kwangnamjin chestradiographsandctfindingsduringhealthcareworkerstuberculosisscreeningusinginterferongammareleaseassayretrospectiveobservationalstudy
_version_	1718407409639096320

Chest Radiographs and CT Findings during Healthcare Workers’ Tuberculosis Screening Using Interferon- Gamma Release Assay: Retrospective Observational Study

Ejemplares similares