Assessment of Anti-Streptolysin O Titre in Healthy School Age Children in El Behira Governorate

Background: Group-A streptococcal serology is used for post-streptococcal disease diagnoses, such as acute rheumatic fever, and occasionally for diagnosis of streptococcal pharyngitis. The prevalence of rheumatic fever in school children aged 6 to 15 years ranges between 0.2 to 0.75 per 1000 childre...

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Autores principales:	Mona Kordy, mohamed zannoun, Magdy El Ghanam
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2020
Materias:	group a streptococci anti-streptolysin o upper limit of normal children el behira Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/777eed4911954511b7ab67bd90014025
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spelling	oai:doaj.org-article:777eed4911954511b7ab67bd900140252021-12-02T15:22:19ZAssessment of Anti-Streptolysin O Titre in Healthy School Age Children in El Behira Governorate2636-41742682-378010.21608/ijma.2020.23002.1089https://doaj.org/article/777eed4911954511b7ab67bd900140252020-07-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_91606_7ae14891c03e683689bf5815812e6b0f.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Group-A streptococcal serology is used for post-streptococcal disease diagnoses, such as acute rheumatic fever, and occasionally for diagnosis of streptococcal pharyngitis. The prevalence of rheumatic fever in school children aged 6 to 15 years ranges between 0.2 to 0.75 per 1000 children per year. The prevalence of rheumatic heart disease in 1000 children ranges from 1 to 5.4. Aim of the work: To determine upper limit of the normal range of Antistreptolysin O titre in healthy school children, aged 6-15 years old in El Behira governorate. Patients and Methods:A cross-sectional study had been performed in EL Behira Governorate and the collected sample were tested in clinical pathology Lab [Al-Azhar University Hospital, Damietta]. A total of 3000 [1609 Males, 1391 Females] serum samples had been collected from children aged 6-15 years, had been tested for Anti-streptolysin O titer [ASO] by turbidimetry. Results: Normal value for the ASO titer rose sharply during early childhood and then declined gradually with age. The estimated titer that was 80% of the upper limit or normal at age 10 years was 287 IU/ml for ASO. Conclusion: This study provides the upper limit of normal value for ASO titre of school children. The "more than 400" rating should instruct clinicians in the treatment of post-streptococcal diseases in patients and provide valuable longitudinal evidence for potential intervention trials against streptococcal diseases in group A.Mona Kordymohamed zannounMagdy El GhanamAl-Azhar University, Faculty of Medicine (Damietta)articlegroup a streptococcianti-streptolysin oupper limit of normalchildrenel behiraMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 3, Pp 625-630 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	group a streptococci anti-streptolysin o upper limit of normal children el behira Medicine (General) R5-920
spellingShingle	group a streptococci anti-streptolysin o upper limit of normal children el behira Medicine (General) R5-920 Mona Kordy mohamed zannoun Magdy El Ghanam Assessment of Anti-Streptolysin O Titre in Healthy School Age Children in El Behira Governorate
description	Background: Group-A streptococcal serology is used for post-streptococcal disease diagnoses, such as acute rheumatic fever, and occasionally for diagnosis of streptococcal pharyngitis. The prevalence of rheumatic fever in school children aged 6 to 15 years ranges between 0.2 to 0.75 per 1000 children per year. The prevalence of rheumatic heart disease in 1000 children ranges from 1 to 5.4. Aim of the work: To determine upper limit of the normal range of Antistreptolysin O titre in healthy school children, aged 6-15 years old in El Behira governorate. Patients and Methods:A cross-sectional study had been performed in EL Behira Governorate and the collected sample were tested in clinical pathology Lab [Al-Azhar University Hospital, Damietta]. A total of 3000 [1609 Males, 1391 Females] serum samples had been collected from children aged 6-15 years, had been tested for Anti-streptolysin O titer [ASO] by turbidimetry. Results: Normal value for the ASO titer rose sharply during early childhood and then declined gradually with age. The estimated titer that was 80% of the upper limit or normal at age 10 years was 287 IU/ml for ASO. Conclusion: This study provides the upper limit of normal value for ASO titre of school children. The "more than 400" rating should instruct clinicians in the treatment of post-streptococcal diseases in patients and provide valuable longitudinal evidence for potential intervention trials against streptococcal diseases in group A.
format	article
author	Mona Kordy mohamed zannoun Magdy El Ghanam
author_facet	Mona Kordy mohamed zannoun Magdy El Ghanam
author_sort	Mona Kordy
title	Assessment of Anti-Streptolysin O Titre in Healthy School Age Children in El Behira Governorate
title_short	Assessment of Anti-Streptolysin O Titre in Healthy School Age Children in El Behira Governorate
title_full	Assessment of Anti-Streptolysin O Titre in Healthy School Age Children in El Behira Governorate
title_fullStr	Assessment of Anti-Streptolysin O Titre in Healthy School Age Children in El Behira Governorate
title_full_unstemmed	Assessment of Anti-Streptolysin O Titre in Healthy School Age Children in El Behira Governorate
title_sort	assessment of anti-streptolysin o titre in healthy school age children in el behira governorate
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2020
url	https://doaj.org/article/777eed4911954511b7ab67bd90014025
work_keys_str_mv	AT monakordy assessmentofantistreptolysinotitreinhealthyschoolagechildreninelbehiragovernorate AT mohamedzannoun assessmentofantistreptolysinotitreinhealthyschoolagechildreninelbehiragovernorate AT magdyelghanam assessmentofantistreptolysinotitreinhealthyschoolagechildreninelbehiragovernorate
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Assessment of Anti-Streptolysin O Titre in Healthy School Age Children in El Behira Governorate

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