The Prescription of Drug Ontology 2.0 (PDRO): More Than the Sum of Its Parts

While drugs and related products have profoundly changed the lives of people around the world, ongoing challenges remain, including inappropriate use of a drug product. Inappropriate uses can be explained in part by ambiguous or incomplete information, for example, missing reasons for treatments, am...

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Autores principales:	Jean-François Ethier, François Goyer, Paul Fabry, Adrien Barton
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	drug ontology drug prescription optimization of prescription medication management ontology development data annotation Medicine R
Acceso en línea:	https://doaj.org/article/778fbcb3e5d4410c8592f13a3b61123f
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id	oai:doaj.org-article:778fbcb3e5d4410c8592f13a3b61123f
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spelling	oai:doaj.org-article:778fbcb3e5d4410c8592f13a3b61123f2021-11-25T17:50:24ZThe Prescription of Drug Ontology 2.0 (PDRO): More Than the Sum of Its Parts10.3390/ijerph1822120251660-46011661-7827https://doaj.org/article/778fbcb3e5d4410c8592f13a3b61123f2021-11-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/22/12025https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601While drugs and related products have profoundly changed the lives of people around the world, ongoing challenges remain, including inappropriate use of a drug product. Inappropriate uses can be explained in part by ambiguous or incomplete information, for example, missing reasons for treatments, ambiguous information on how to take a medication, or lack of information on medication-related events outside the health care system. In order to fully assess the situation, data from multiple systems (electronic medical records, pharmacy and radiology information systems, laboratory management systems, etc.) from multiple organizations (outpatient clinics, hospitals, long-term care facilities, laboratories, pharmacies, registries, governments) on a large geographical scale is needed. Formal knowledge models like ontologies can help address such an information integration challenge. Existing approaches like the Observational Medical Outcomes Partnership are discussed and contrasted with the use of ontologies and systems using them for data integration. The PRescription Drug Ontology 2.0 (PDRO 2.0) is then presented and entities that are paramount in addressing this problematic are described. Finally, the benefits of using PDRO are discussed through a series of exemplar situation.Jean-François EthierFrançois GoyerPaul FabryAdrien BartonMDPI AGarticledrug ontologydrug prescriptionoptimization of prescriptionmedication managementontology developmentdata annotationMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 12025, p 12025 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	drug ontology drug prescription optimization of prescription medication management ontology development data annotation Medicine R
spellingShingle	drug ontology drug prescription optimization of prescription medication management ontology development data annotation Medicine R Jean-François Ethier François Goyer Paul Fabry Adrien Barton The Prescription of Drug Ontology 2.0 (PDRO): More Than the Sum of Its Parts
description	While drugs and related products have profoundly changed the lives of people around the world, ongoing challenges remain, including inappropriate use of a drug product. Inappropriate uses can be explained in part by ambiguous or incomplete information, for example, missing reasons for treatments, ambiguous information on how to take a medication, or lack of information on medication-related events outside the health care system. In order to fully assess the situation, data from multiple systems (electronic medical records, pharmacy and radiology information systems, laboratory management systems, etc.) from multiple organizations (outpatient clinics, hospitals, long-term care facilities, laboratories, pharmacies, registries, governments) on a large geographical scale is needed. Formal knowledge models like ontologies can help address such an information integration challenge. Existing approaches like the Observational Medical Outcomes Partnership are discussed and contrasted with the use of ontologies and systems using them for data integration. The PRescription Drug Ontology 2.0 (PDRO 2.0) is then presented and entities that are paramount in addressing this problematic are described. Finally, the benefits of using PDRO are discussed through a series of exemplar situation.
format	article
author	Jean-François Ethier François Goyer Paul Fabry Adrien Barton
author_facet	Jean-François Ethier François Goyer Paul Fabry Adrien Barton
author_sort	Jean-François Ethier
title	The Prescription of Drug Ontology 2.0 (PDRO): More Than the Sum of Its Parts
title_short	The Prescription of Drug Ontology 2.0 (PDRO): More Than the Sum of Its Parts
title_full	The Prescription of Drug Ontology 2.0 (PDRO): More Than the Sum of Its Parts
title_fullStr	The Prescription of Drug Ontology 2.0 (PDRO): More Than the Sum of Its Parts
title_full_unstemmed	The Prescription of Drug Ontology 2.0 (PDRO): More Than the Sum of Its Parts
title_sort	prescription of drug ontology 2.0 (pdro): more than the sum of its parts
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/778fbcb3e5d4410c8592f13a3b61123f
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The Prescription of Drug Ontology 2.0 (PDRO): More Than the Sum of Its Parts

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