Structural genomics approach to investigate deleterious impact of nsSNPs in conserved telomere maintenance component 1
Abstract Conserved telomere maintenance component 1 (CTC1) is an important component of the CST (CTC1-STN1-TEN1) complex, involved in maintaining the stability of telomeric DNA. Several non-synonymous single-nucleotide polymorphisms (nsSNPs) in CTC1 have been reported to cause Coats plus syndrome an...
Guardado en:
Autores principales: | Arunabh Choudhury, Taj Mohammad, Nikhil Samarth, Afzal Hussain, Md. Tabish Rehman, Asimul Islam, Mohamed F. Alajmi, Shailza Singh, Md. Imtaiyaz Hassan |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/778ff0f482034cf3800d06584dcf9a28 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Pathogenic nsSNPs that increase the risks of cancers among the Orang Asli and Malays
por: Nurul Ain Khoruddin, et al.
Publicado: (2021) -
A comprehensive in silico investigation into the nsSNPs of Drd2 gene predicts significant functional consequences in dopamine signaling and pharmacotherapy
por: Samia Sultana Lira, et al.
Publicado: (2021) -
In silico analysis predicting effects of deleterious SNPs of human RASSF5 gene on its structure and functions
por: Md. Shahadat Hossain, et al.
Publicado: (2020) -
In silico analyses of deleterious missense SNPs of human apolipoprotein E3
por: Allan S. Pires, et al.
Publicado: (2017) -
Interaction of polyethylene glycol with cytochrome c investigated via in vitro and in silico approaches
por: Zahoor Ahmad Parray, et al.
Publicado: (2021)