Solid-Phase Extraction of Active Compounds from Natural Products by Molecularly Imprinted Polymers: Synthesis and Extraction Parameters

Molecularly imprinted polymers (MIPs) are synthetic polymers with a predetermined selectivity for a particular analyte or group of structurally related compounds, making them ideal materials for separation processes. Hence, in sample preparation, MIPs are chosen as an excellent material to provide s...

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Bibliographic Details
Main Authors: Sazlinda Kamaruzaman, Najihah Mohammad Nasir, Siti Munirah Mohd Faudzi, Noorfatimah Yahaya, Nor Suhaila Mohamad Hanapi, Wan Nazihah Wan Ibrahim
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/7797e73d5bff49cca25cc9b1bc9ff355
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Summary:Molecularly imprinted polymers (MIPs) are synthetic polymers with a predetermined selectivity for a particular analyte or group of structurally related compounds, making them ideal materials for separation processes. Hence, in sample preparation, MIPs are chosen as an excellent material to provide selectivity. Moreover, its use in solid-phase extraction, also referred to as molecular imprinted solid phase extraction (MISPE), is well regarded. In recent years, many papers have been published addressing the utilization of MIPs or MISPE as sorbents in natural product applications, such as synthesis. This review describes the synthesis and characterization of MIPs as a tool in natural product applications.