Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation

Stimulation of peripheral nerve activity may be used to treat metabolic and inflammatory disorders, but current approaches need implanted devices. Here, the authors present a non-invasive approach, and show that ultrasound-mediated stimulation can be targeted to specific sub-organ locations in precl...

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Autores principales: Victoria Cotero, Ying Fan, Tea Tsaava, Adam M. Kressel, Ileana Hancu, Paul Fitzgerald, Kirk Wallace, Sireesha Kaanumalle, John Graf, Wayne Rigby, Tzu-Jen Kao, Jeanette Roberts, Chitresh Bhushan, Suresh Joel, Thomas R. Coleman, Stavros Zanos, Kevin J. Tracey, Jeffrey Ashe, Sangeeta S. Chavan, Christopher Puleo
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/77a64eba47a04d5e919deb62157049e8
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spelling oai:doaj.org-article:77a64eba47a04d5e919deb62157049e82021-12-02T17:02:10ZNoninvasive sub-organ ultrasound stimulation for targeted neuromodulation10.1038/s41467-019-08750-92041-1723https://doaj.org/article/77a64eba47a04d5e919deb62157049e82019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08750-9https://doaj.org/toc/2041-1723Stimulation of peripheral nerve activity may be used to treat metabolic and inflammatory disorders, but current approaches need implanted devices. Here, the authors present a non-invasive approach, and show that ultrasound-mediated stimulation can be targeted to specific sub-organ locations in preclinical models and alter the response of metabolic and inflammatory neural pathways.Victoria CoteroYing FanTea TsaavaAdam M. KresselIleana HancuPaul FitzgeraldKirk WallaceSireesha KaanumalleJohn GrafWayne RigbyTzu-Jen KaoJeanette RobertsChitresh BhushanSuresh JoelThomas R. ColemanStavros ZanosKevin J. TraceyJeffrey AsheSangeeta S. ChavanChristopher PuleoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Victoria Cotero
Ying Fan
Tea Tsaava
Adam M. Kressel
Ileana Hancu
Paul Fitzgerald
Kirk Wallace
Sireesha Kaanumalle
John Graf
Wayne Rigby
Tzu-Jen Kao
Jeanette Roberts
Chitresh Bhushan
Suresh Joel
Thomas R. Coleman
Stavros Zanos
Kevin J. Tracey
Jeffrey Ashe
Sangeeta S. Chavan
Christopher Puleo
Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation
description Stimulation of peripheral nerve activity may be used to treat metabolic and inflammatory disorders, but current approaches need implanted devices. Here, the authors present a non-invasive approach, and show that ultrasound-mediated stimulation can be targeted to specific sub-organ locations in preclinical models and alter the response of metabolic and inflammatory neural pathways.
format article
author Victoria Cotero
Ying Fan
Tea Tsaava
Adam M. Kressel
Ileana Hancu
Paul Fitzgerald
Kirk Wallace
Sireesha Kaanumalle
John Graf
Wayne Rigby
Tzu-Jen Kao
Jeanette Roberts
Chitresh Bhushan
Suresh Joel
Thomas R. Coleman
Stavros Zanos
Kevin J. Tracey
Jeffrey Ashe
Sangeeta S. Chavan
Christopher Puleo
author_facet Victoria Cotero
Ying Fan
Tea Tsaava
Adam M. Kressel
Ileana Hancu
Paul Fitzgerald
Kirk Wallace
Sireesha Kaanumalle
John Graf
Wayne Rigby
Tzu-Jen Kao
Jeanette Roberts
Chitresh Bhushan
Suresh Joel
Thomas R. Coleman
Stavros Zanos
Kevin J. Tracey
Jeffrey Ashe
Sangeeta S. Chavan
Christopher Puleo
author_sort Victoria Cotero
title Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation
title_short Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation
title_full Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation
title_fullStr Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation
title_full_unstemmed Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation
title_sort noninvasive sub-organ ultrasound stimulation for targeted neuromodulation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/77a64eba47a04d5e919deb62157049e8
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