Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration

The mechanisms regulating regeneration of the earthworm are unclear. Here, the authors use genomic and transcriptomic analysis of the earthworm Eisenia andrei together with Hi-C analysis to identify genes involved and show activation of LINE2 transposable elements on regeneration.

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Autores principales: Yong Shao, Xiao-Bo Wang, Jin-Jin Zhang, Ming-Li Li, Shou-Song Wu, Xi-Yao Ma, Xue Wang, Hui-Fang Zhao, Yuan Li, Helen He Zhu, David M. Irwin, De-Peng Wang, Guo-Jie Zhang, Jue Ruan, Dong-Dong Wu
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/77b6e7eb77fc4c318af25ab3aff26d5b
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spelling oai:doaj.org-article:77b6e7eb77fc4c318af25ab3aff26d5b2021-12-02T14:47:29ZGenome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration10.1038/s41467-020-16454-82041-1723https://doaj.org/article/77b6e7eb77fc4c318af25ab3aff26d5b2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16454-8https://doaj.org/toc/2041-1723The mechanisms regulating regeneration of the earthworm are unclear. Here, the authors use genomic and transcriptomic analysis of the earthworm Eisenia andrei together with Hi-C analysis to identify genes involved and show activation of LINE2 transposable elements on regeneration.Yong ShaoXiao-Bo WangJin-Jin ZhangMing-Li LiShou-Song WuXi-Yao MaXue WangHui-Fang ZhaoYuan LiHelen He ZhuDavid M. IrwinDe-Peng WangGuo-Jie ZhangJue RuanDong-Dong WuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yong Shao
Xiao-Bo Wang
Jin-Jin Zhang
Ming-Li Li
Shou-Song Wu
Xi-Yao Ma
Xue Wang
Hui-Fang Zhao
Yuan Li
Helen He Zhu
David M. Irwin
De-Peng Wang
Guo-Jie Zhang
Jue Ruan
Dong-Dong Wu
Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration
description The mechanisms regulating regeneration of the earthworm are unclear. Here, the authors use genomic and transcriptomic analysis of the earthworm Eisenia andrei together with Hi-C analysis to identify genes involved and show activation of LINE2 transposable elements on regeneration.
format article
author Yong Shao
Xiao-Bo Wang
Jin-Jin Zhang
Ming-Li Li
Shou-Song Wu
Xi-Yao Ma
Xue Wang
Hui-Fang Zhao
Yuan Li
Helen He Zhu
David M. Irwin
De-Peng Wang
Guo-Jie Zhang
Jue Ruan
Dong-Dong Wu
author_facet Yong Shao
Xiao-Bo Wang
Jin-Jin Zhang
Ming-Li Li
Shou-Song Wu
Xi-Yao Ma
Xue Wang
Hui-Fang Zhao
Yuan Li
Helen He Zhu
David M. Irwin
De-Peng Wang
Guo-Jie Zhang
Jue Ruan
Dong-Dong Wu
author_sort Yong Shao
title Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration
title_short Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration
title_full Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration
title_fullStr Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration
title_full_unstemmed Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration
title_sort genome and single-cell rna-sequencing of the earthworm eisenia andrei identifies cellular mechanisms underlying regeneration
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/77b6e7eb77fc4c318af25ab3aff26d5b
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