Liver-derived ketone bodies are necessary for food anticipation

Food anticipation is thought to be initiated by the central clock in the brain. Here the authors show that the peripheral organs initiate this process by showing that liver-specific deletion of Per2 can inhibit food anticipation by interfering with ß-hydroxybutyrate production and its subsequent pro...

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Autores principales: Rohit Chavan, Céline Feillet, Sara S. Fonseca Costa, James E. Delorme, Takashi Okabe, Jürgen A. Ripperger, Urs Albrecht
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/77b85e39911340e4b93f1f36a10c9087
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spelling oai:doaj.org-article:77b85e39911340e4b93f1f36a10c90872021-12-02T15:35:00ZLiver-derived ketone bodies are necessary for food anticipation10.1038/ncomms105802041-1723https://doaj.org/article/77b85e39911340e4b93f1f36a10c90872016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10580https://doaj.org/toc/2041-1723Food anticipation is thought to be initiated by the central clock in the brain. Here the authors show that the peripheral organs initiate this process by showing that liver-specific deletion of Per2 can inhibit food anticipation by interfering with ß-hydroxybutyrate production and its subsequent processing in the brain.Rohit ChavanCéline FeilletSara S. Fonseca CostaJames E. DelormeTakashi OkabeJürgen A. RippergerUrs AlbrechtNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rohit Chavan
Céline Feillet
Sara S. Fonseca Costa
James E. Delorme
Takashi Okabe
Jürgen A. Ripperger
Urs Albrecht
Liver-derived ketone bodies are necessary for food anticipation
description Food anticipation is thought to be initiated by the central clock in the brain. Here the authors show that the peripheral organs initiate this process by showing that liver-specific deletion of Per2 can inhibit food anticipation by interfering with ß-hydroxybutyrate production and its subsequent processing in the brain.
format article
author Rohit Chavan
Céline Feillet
Sara S. Fonseca Costa
James E. Delorme
Takashi Okabe
Jürgen A. Ripperger
Urs Albrecht
author_facet Rohit Chavan
Céline Feillet
Sara S. Fonseca Costa
James E. Delorme
Takashi Okabe
Jürgen A. Ripperger
Urs Albrecht
author_sort Rohit Chavan
title Liver-derived ketone bodies are necessary for food anticipation
title_short Liver-derived ketone bodies are necessary for food anticipation
title_full Liver-derived ketone bodies are necessary for food anticipation
title_fullStr Liver-derived ketone bodies are necessary for food anticipation
title_full_unstemmed Liver-derived ketone bodies are necessary for food anticipation
title_sort liver-derived ketone bodies are necessary for food anticipation
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/77b85e39911340e4b93f1f36a10c9087
work_keys_str_mv AT rohitchavan liverderivedketonebodiesarenecessaryforfoodanticipation
AT celinefeillet liverderivedketonebodiesarenecessaryforfoodanticipation
AT sarasfonsecacosta liverderivedketonebodiesarenecessaryforfoodanticipation
AT jamesedelorme liverderivedketonebodiesarenecessaryforfoodanticipation
AT takashiokabe liverderivedketonebodiesarenecessaryforfoodanticipation
AT jurgenaripperger liverderivedketonebodiesarenecessaryforfoodanticipation
AT ursalbrecht liverderivedketonebodiesarenecessaryforfoodanticipation
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