Liver-derived ketone bodies are necessary for food anticipation

Food anticipation is thought to be initiated by the central clock in the brain. Here the authors show that the peripheral organs initiate this process by showing that liver-specific deletion of Per2 can inhibit food anticipation by interfering with ß-hydroxybutyrate production and its subsequent pro...

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Main Authors:	Rohit Chavan, Céline Feillet, Sara S. Fonseca Costa, James E. Delorme, Takashi Okabe, Jürgen A. Ripperger, Urs Albrecht
Format:	article
Language:	EN
Published:	Nature Portfolio 2016
Subjects:	Science Q
Online Access:	https://doaj.org/article/77b85e39911340e4b93f1f36a10c9087
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id	oai:doaj.org-article:77b85e39911340e4b93f1f36a10c9087
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spelling	oai:doaj.org-article:77b85e39911340e4b93f1f36a10c90872021-12-02T15:35:00ZLiver-derived ketone bodies are necessary for food anticipation10.1038/ncomms105802041-1723https://doaj.org/article/77b85e39911340e4b93f1f36a10c90872016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10580https://doaj.org/toc/2041-1723Food anticipation is thought to be initiated by the central clock in the brain. Here the authors show that the peripheral organs initiate this process by showing that liver-specific deletion of Per2 can inhibit food anticipation by interfering with ß-hydroxybutyrate production and its subsequent processing in the brain.Rohit ChavanCéline FeilletSara S. Fonseca CostaJames E. DelormeTakashi OkabeJürgen A. RippergerUrs AlbrechtNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rohit Chavan Céline Feillet Sara S. Fonseca Costa James E. Delorme Takashi Okabe Jürgen A. Ripperger Urs Albrecht Liver-derived ketone bodies are necessary for food anticipation
description	Food anticipation is thought to be initiated by the central clock in the brain. Here the authors show that the peripheral organs initiate this process by showing that liver-specific deletion of Per2 can inhibit food anticipation by interfering with ß-hydroxybutyrate production and its subsequent processing in the brain.
format	article
author	Rohit Chavan Céline Feillet Sara S. Fonseca Costa James E. Delorme Takashi Okabe Jürgen A. Ripperger Urs Albrecht
author_facet	Rohit Chavan Céline Feillet Sara S. Fonseca Costa James E. Delorme Takashi Okabe Jürgen A. Ripperger Urs Albrecht
author_sort	Rohit Chavan
title	Liver-derived ketone bodies are necessary for food anticipation
title_short	Liver-derived ketone bodies are necessary for food anticipation
title_full	Liver-derived ketone bodies are necessary for food anticipation
title_fullStr	Liver-derived ketone bodies are necessary for food anticipation
title_full_unstemmed	Liver-derived ketone bodies are necessary for food anticipation
title_sort	liver-derived ketone bodies are necessary for food anticipation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/77b85e39911340e4b93f1f36a10c9087
work_keys_str_mv	AT rohitchavan liverderivedketonebodiesarenecessaryforfoodanticipation AT celinefeillet liverderivedketonebodiesarenecessaryforfoodanticipation AT sarasfonsecacosta liverderivedketonebodiesarenecessaryforfoodanticipation AT jamesedelorme liverderivedketonebodiesarenecessaryforfoodanticipation AT takashiokabe liverderivedketonebodiesarenecessaryforfoodanticipation AT jurgenaripperger liverderivedketonebodiesarenecessaryforfoodanticipation AT ursalbrecht liverderivedketonebodiesarenecessaryforfoodanticipation
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Liver-derived ketone bodies are necessary for food anticipation

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