Liver-derived ketone bodies are necessary for food anticipation
Food anticipation is thought to be initiated by the central clock in the brain. Here the authors show that the peripheral organs initiate this process by showing that liver-specific deletion of Per2 can inhibit food anticipation by interfering with ß-hydroxybutyrate production and its subsequent pro...
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Nature Portfolio
2016
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oai:doaj.org-article:77b85e39911340e4b93f1f36a10c90872021-12-02T15:35:00ZLiver-derived ketone bodies are necessary for food anticipation10.1038/ncomms105802041-1723https://doaj.org/article/77b85e39911340e4b93f1f36a10c90872016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10580https://doaj.org/toc/2041-1723Food anticipation is thought to be initiated by the central clock in the brain. Here the authors show that the peripheral organs initiate this process by showing that liver-specific deletion of Per2 can inhibit food anticipation by interfering with ß-hydroxybutyrate production and its subsequent processing in the brain.Rohit ChavanCéline FeilletSara S. Fonseca CostaJames E. DelormeTakashi OkabeJürgen A. RippergerUrs AlbrechtNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
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Science Q Rohit Chavan Céline Feillet Sara S. Fonseca Costa James E. Delorme Takashi Okabe Jürgen A. Ripperger Urs Albrecht Liver-derived ketone bodies are necessary for food anticipation |
description |
Food anticipation is thought to be initiated by the central clock in the brain. Here the authors show that the peripheral organs initiate this process by showing that liver-specific deletion of Per2 can inhibit food anticipation by interfering with ß-hydroxybutyrate production and its subsequent processing in the brain. |
format |
article |
author |
Rohit Chavan Céline Feillet Sara S. Fonseca Costa James E. Delorme Takashi Okabe Jürgen A. Ripperger Urs Albrecht |
author_facet |
Rohit Chavan Céline Feillet Sara S. Fonseca Costa James E. Delorme Takashi Okabe Jürgen A. Ripperger Urs Albrecht |
author_sort |
Rohit Chavan |
title |
Liver-derived ketone bodies are necessary for food anticipation |
title_short |
Liver-derived ketone bodies are necessary for food anticipation |
title_full |
Liver-derived ketone bodies are necessary for food anticipation |
title_fullStr |
Liver-derived ketone bodies are necessary for food anticipation |
title_full_unstemmed |
Liver-derived ketone bodies are necessary for food anticipation |
title_sort |
liver-derived ketone bodies are necessary for food anticipation |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/77b85e39911340e4b93f1f36a10c9087 |
work_keys_str_mv |
AT rohitchavan liverderivedketonebodiesarenecessaryforfoodanticipation AT celinefeillet liverderivedketonebodiesarenecessaryforfoodanticipation AT sarasfonsecacosta liverderivedketonebodiesarenecessaryforfoodanticipation AT jamesedelorme liverderivedketonebodiesarenecessaryforfoodanticipation AT takashiokabe liverderivedketonebodiesarenecessaryforfoodanticipation AT jurgenaripperger liverderivedketonebodiesarenecessaryforfoodanticipation AT ursalbrecht liverderivedketonebodiesarenecessaryforfoodanticipation |
_version_ |
1718386663595442176 |