Gene network revealed involvements of Birc2, Birc3 and Tnfrsf1a in anti-apoptosis of injured peripheral nerves.
Crush injury or axotomy of peripheral nerves results in the rapid production of the inflammatory cytokines, which were confirmed in various models, to some extent, to be noxious to the myelin sheath or Schwann cells (SCs). TNF-α is one of the primary initiators of the inflammatory cascade and exerts...
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Main Authors: | Yongjun Wang, Xin Tang, Bin Yu, Yun Gu, Ying Yuan, Dengbing Yao, Fei Ding, Xiaosong Gu |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/77c19a124173440db67fb11f3c413958 |
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