MARKERS OF SYSTEMIC INFLAMMATION AND MATRIX METALLOPROTEINASE / TISSUE INHIBITOR OF METALLOPROTEINASES SYSTEM AT DIFFERENT STAGES OF CHRONIC HEART FAILURE

Abstract. A comparative analysis of endotoxinemia grade, tumor necrosis factor α, C-reactive protein, sEselectin, matrix metalloproteinase-9 (MMP) and tissue inhibitor of metalloproteinases-4 (TIMP) levels was performed in a group of patients with chronic heart failure (CHF). An association has been...

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Autores principales:	E. N. Egorova, M. A. Kuzmina, V. V. Masur, M. N. Kalinkin, E. S. Mazur
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	chronic heart failure pathogenesis chronic systemic inflammation endotoxin proinflammatory cytokines matrix metalloproteinases Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/77c253dfa7cb4d95a71c6bc9aba39971
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spelling	oai:doaj.org-article:77c253dfa7cb4d95a71c6bc9aba399712021-11-18T08:03:40ZMARKERS OF SYSTEMIC INFLAMMATION AND MATRIX METALLOPROTEINASE / TISSUE INHIBITOR OF METALLOPROTEINASES SYSTEM AT DIFFERENT STAGES OF CHRONIC HEART FAILURE1563-06252313-741X10.15789/1563-0625-2012-1-2-139-142https://doaj.org/article/77c253dfa7cb4d95a71c6bc9aba399712014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/314https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. A comparative analysis of endotoxinemia grade, tumor necrosis factor α, C-reactive protein, sEselectin, matrix metalloproteinase-9 (MMP) and tissue inhibitor of metalloproteinases-4 (TIMP) levels was performed in a group of patients with chronic heart failure (CHF). An association has been shown between CHF progression and activation of systemic inflammation, like as with an imbalance in MMP/TIMP system. These alterations may represent a factor of structural disturbances in myocardial extracellular matrix, and promote a compartmental heart remodeling in this disorder.E. N. EgorovaM. A. KuzminaV. V. MasurM. N. KalinkinE. S. MazurSPb RAACIarticlechronic heart failure pathogenesischronic systemic inflammationendotoxinproinflammatory cytokinesmatrix metalloproteinasesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 14, Iss 1-2, Pp 139-142 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	chronic heart failure pathogenesis chronic systemic inflammation endotoxin proinflammatory cytokines matrix metalloproteinases Immunologic diseases. Allergy RC581-607
spellingShingle	chronic heart failure pathogenesis chronic systemic inflammation endotoxin proinflammatory cytokines matrix metalloproteinases Immunologic diseases. Allergy RC581-607 E. N. Egorova M. A. Kuzmina V. V. Masur M. N. Kalinkin E. S. Mazur MARKERS OF SYSTEMIC INFLAMMATION AND MATRIX METALLOPROTEINASE / TISSUE INHIBITOR OF METALLOPROTEINASES SYSTEM AT DIFFERENT STAGES OF CHRONIC HEART FAILURE
description	Abstract. A comparative analysis of endotoxinemia grade, tumor necrosis factor α, C-reactive protein, sEselectin, matrix metalloproteinase-9 (MMP) and tissue inhibitor of metalloproteinases-4 (TIMP) levels was performed in a group of patients with chronic heart failure (CHF). An association has been shown between CHF progression and activation of systemic inflammation, like as with an imbalance in MMP/TIMP system. These alterations may represent a factor of structural disturbances in myocardial extracellular matrix, and promote a compartmental heart remodeling in this disorder.
format	article
author	E. N. Egorova M. A. Kuzmina V. V. Masur M. N. Kalinkin E. S. Mazur
author_facet	E. N. Egorova M. A. Kuzmina V. V. Masur M. N. Kalinkin E. S. Mazur
author_sort	E. N. Egorova
title	MARKERS OF SYSTEMIC INFLAMMATION AND MATRIX METALLOPROTEINASE / TISSUE INHIBITOR OF METALLOPROTEINASES SYSTEM AT DIFFERENT STAGES OF CHRONIC HEART FAILURE
title_short	MARKERS OF SYSTEMIC INFLAMMATION AND MATRIX METALLOPROTEINASE / TISSUE INHIBITOR OF METALLOPROTEINASES SYSTEM AT DIFFERENT STAGES OF CHRONIC HEART FAILURE
title_full	MARKERS OF SYSTEMIC INFLAMMATION AND MATRIX METALLOPROTEINASE / TISSUE INHIBITOR OF METALLOPROTEINASES SYSTEM AT DIFFERENT STAGES OF CHRONIC HEART FAILURE
title_fullStr	MARKERS OF SYSTEMIC INFLAMMATION AND MATRIX METALLOPROTEINASE / TISSUE INHIBITOR OF METALLOPROTEINASES SYSTEM AT DIFFERENT STAGES OF CHRONIC HEART FAILURE
title_full_unstemmed	MARKERS OF SYSTEMIC INFLAMMATION AND MATRIX METALLOPROTEINASE / TISSUE INHIBITOR OF METALLOPROTEINASES SYSTEM AT DIFFERENT STAGES OF CHRONIC HEART FAILURE
title_sort	markers of systemic inflammation and matrix metalloproteinase / tissue inhibitor of metalloproteinases system at different stages of chronic heart failure
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/77c253dfa7cb4d95a71c6bc9aba39971
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MARKERS OF SYSTEMIC INFLAMMATION AND MATRIX METALLOPROTEINASE / TISSUE INHIBITOR OF METALLOPROTEINASES SYSTEM AT DIFFERENT STAGES OF CHRONIC HEART FAILURE

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