Rare Case of Bilateral Diffuse Uveal Melanocytic Proliferation with Dermal and Mucosal Hyperpigmentations

Purpose: The demonstration of a rare case of bilateral diffuse uveal melanocytic proliferation (BDUMP) due to a lung carcinoma with unusual dermal lesions. Case description: A 76-year-old man with painless bilateral vision loss revealed leopard or giraffe spot chorioretinopathy and bilateral serous...

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Autores principales:	Michelle Prasuhn, Nathalie Rommel, Vinodh Kakkassery, Salvatore Grisanti, Mahdy Ranjbar, Felix Rommel
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	bilateral diffuse uveal melanocytic proliferation dermal hyperpigmentation mucosal hyperpigmentation serous retinal detachment leopard spot chorioretinitis lung carcinoma Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/77d33ad1bda74bfdbe969ba37fcbef6f
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spelling	oai:doaj.org-article:77d33ad1bda74bfdbe969ba37fcbef6f2021-11-25T17:21:11ZRare Case of Bilateral Diffuse Uveal Melanocytic Proliferation with Dermal and Mucosal Hyperpigmentations10.3390/diagnostics111120522075-4418https://doaj.org/article/77d33ad1bda74bfdbe969ba37fcbef6f2021-11-01T00:00:00Zhttps://www.mdpi.com/2075-4418/11/11/2052https://doaj.org/toc/2075-4418Purpose: The demonstration of a rare case of bilateral diffuse uveal melanocytic proliferation (BDUMP) due to a lung carcinoma with unusual dermal lesions. Case description: A 76-year-old man with painless bilateral vision loss revealed leopard or giraffe spot chorioretinopathy and bilateral serous retinal detachment. Ultrasound biomicroscopy revealed uveal swelling expanding into the anterior chamber angle. Dermal and mucosal lesions were present on the lip, breast, groin, scrotum, and penis. Screening analyses revealed a non-small cell lung carcinoma. Conclusions: The diagnosis of BDUMP, a rare paraneoplastic syndrome, was made. The ophthalmological diagnosis led to screening investigations and revealed the underlying malignant disease. Uncommonly, multiple dermal and mucosal lesions could be detected and were analyzed histopathologically.Michelle PrasuhnNathalie RommelVinodh KakkasserySalvatore GrisantiMahdy RanjbarFelix RommelMDPI AGarticlebilateral diffuse uveal melanocytic proliferationdermal hyperpigmentationmucosal hyperpigmentationserous retinal detachmentleopard spot chorioretinitislung carcinomaMedicine (General)R5-920ENDiagnostics, Vol 11, Iss 2052, p 2052 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	bilateral diffuse uveal melanocytic proliferation dermal hyperpigmentation mucosal hyperpigmentation serous retinal detachment leopard spot chorioretinitis lung carcinoma Medicine (General) R5-920
spellingShingle	bilateral diffuse uveal melanocytic proliferation dermal hyperpigmentation mucosal hyperpigmentation serous retinal detachment leopard spot chorioretinitis lung carcinoma Medicine (General) R5-920 Michelle Prasuhn Nathalie Rommel Vinodh Kakkassery Salvatore Grisanti Mahdy Ranjbar Felix Rommel Rare Case of Bilateral Diffuse Uveal Melanocytic Proliferation with Dermal and Mucosal Hyperpigmentations
description	Purpose: The demonstration of a rare case of bilateral diffuse uveal melanocytic proliferation (BDUMP) due to a lung carcinoma with unusual dermal lesions. Case description: A 76-year-old man with painless bilateral vision loss revealed leopard or giraffe spot chorioretinopathy and bilateral serous retinal detachment. Ultrasound biomicroscopy revealed uveal swelling expanding into the anterior chamber angle. Dermal and mucosal lesions were present on the lip, breast, groin, scrotum, and penis. Screening analyses revealed a non-small cell lung carcinoma. Conclusions: The diagnosis of BDUMP, a rare paraneoplastic syndrome, was made. The ophthalmological diagnosis led to screening investigations and revealed the underlying malignant disease. Uncommonly, multiple dermal and mucosal lesions could be detected and were analyzed histopathologically.
format	article
author	Michelle Prasuhn Nathalie Rommel Vinodh Kakkassery Salvatore Grisanti Mahdy Ranjbar Felix Rommel
author_facet	Michelle Prasuhn Nathalie Rommel Vinodh Kakkassery Salvatore Grisanti Mahdy Ranjbar Felix Rommel
author_sort	Michelle Prasuhn
title	Rare Case of Bilateral Diffuse Uveal Melanocytic Proliferation with Dermal and Mucosal Hyperpigmentations
title_short	Rare Case of Bilateral Diffuse Uveal Melanocytic Proliferation with Dermal and Mucosal Hyperpigmentations
title_full	Rare Case of Bilateral Diffuse Uveal Melanocytic Proliferation with Dermal and Mucosal Hyperpigmentations
title_fullStr	Rare Case of Bilateral Diffuse Uveal Melanocytic Proliferation with Dermal and Mucosal Hyperpigmentations
title_full_unstemmed	Rare Case of Bilateral Diffuse Uveal Melanocytic Proliferation with Dermal and Mucosal Hyperpigmentations
title_sort	rare case of bilateral diffuse uveal melanocytic proliferation with dermal and mucosal hyperpigmentations
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/77d33ad1bda74bfdbe969ba37fcbef6f
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Rare Case of Bilateral Diffuse Uveal Melanocytic Proliferation with Dermal and Mucosal Hyperpigmentations

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